Polarography as a technique of choice for the evaluation of total antioxidant activity: The case study of selected Coprinus Comatus extracts and quinic acid, their antidiabetic ingredient
Само за регистроване кориснике
2021
Аутори
Karaman, MajaTesanovic, Kristina
Gorjanovic, Stanislava
Pastor, Ferenc

Simonovic, Mladen
Glumac, Miodrag
Pejin, Boris

Чланак у часопису (Објављена верзија)

Метаподаци
Приказ свих података о документуАпстракт
This study was focused on in vitro screening of the total antioxidant activity of the selected extracts of the mushroom Coprinus comatus and quinic acid, one of their antidiabetic ingredients, by an uncommon electrochemical assay. Indeed, direct current (DC) polarographic HydroxoPerhydroxo Mercury(II) Complex (HPMC) assay based on decrease of anodic limiting current originating from HPMC formation in alkaline solutions of hydrogen peroxide at potential of mercury dissolution, observed upon gradual addition of antioxidants, was applied herein for the estimation of the natural products' antioxidativity. Quinic acid was found to exhibit most promising antioxidant potential (4.0 ± 0.2%µL-1) being ≈ 2-fold more active than the screened C. comatus extract samples. Actually, such a finding puts some light on the antioxidativity of cyclic polyols, well understimated class of organic compounds, compared to aromatic (poly)phenolics. As a low cost, easy-to handle and accurate this polarographic a...ssay may be thoroughly recommended for much broader use. [Formula: see text].
Кључне речи:
Antioxidants / antioxidativity / Biological Products / Coprinus / cyclic polyols / HPMC assay / Hypoglycemic Agents / Mycelium / polarography / Polarography / quinic acid / Quinic AcidИзвор:
Natural Product Research, 2021, 35, 10, 1711-1716Финансирање / пројекти:
- Биоактивни природни производи самониклих, гајених и јестивих биљака: одређивање структура и активности (RS-172053)
- Биолошки активни природни производи као потенцијални извори нових лекова и дијететских суплемената (RS-172058)
- Интеракције мембрана са унутарћелијским и апопластичним простором: изучавања биоенергетике и сингализације користећи биофизичке и биохемијске методе (RS-173040)
- Биосенсинг технологије и глобални систем за континуирана истраживања и интегрисано управљање екосистемима (RS-43002)
- Модификације антиоксидативног метаболизма биљака са циљем повећања толеранције на абиотски стрес и идентификација нових биомаркера са применом у ремедијацији и мониторингу деградираних станишта (RS-43010)
- Развој и примена нових и традиционалних технологија у производњи конкурентних прехрамбених производа са додатом вредношћу за европско и светско тржиште - Створимо богатство из богатства Србије (RS-46001)
DOI: 10.1080/14786419.2019.1628753
ISSN: 1478-6419
WoS: 000472327300001
Scopus: 2-s2.0-85067613887
Колекције
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Karaman, Maja AU - Tesanovic, Kristina AU - Gorjanovic, Stanislava AU - Pastor, Ferenc AU - Simonovic, Mladen AU - Glumac, Miodrag AU - Pejin, Boris PY - 2021 UR - http://www.ncbi.nlm.nih.gov/pubmed/31192702 UR - http://cherry.chem.bg.ac.rs/handle/123456789/4773 AB - This study was focused on in vitro screening of the total antioxidant activity of the selected extracts of the mushroom Coprinus comatus and quinic acid, one of their antidiabetic ingredients, by an uncommon electrochemical assay. Indeed, direct current (DC) polarographic HydroxoPerhydroxo Mercury(II) Complex (HPMC) assay based on decrease of anodic limiting current originating from HPMC formation in alkaline solutions of hydrogen peroxide at potential of mercury dissolution, observed upon gradual addition of antioxidants, was applied herein for the estimation of the natural products' antioxidativity. Quinic acid was found to exhibit most promising antioxidant potential (4.0 ± 0.2%µL-1) being ≈ 2-fold more active than the screened C. comatus extract samples. Actually, such a finding puts some light on the antioxidativity of cyclic polyols, well understimated class of organic compounds, compared to aromatic (poly)phenolics. As a low cost, easy-to handle and accurate this polarographic assay may be thoroughly recommended for much broader use. [Formula: see text]. T2 - Natural Product Research T1 - Polarography as a technique of choice for the evaluation of total antioxidant activity: The case study of selected Coprinus Comatus extracts and quinic acid, their antidiabetic ingredient VL - 35 IS - 10 SP - 1711 EP - 1716 DO - 10.1080/14786419.2019.1628753 ER -
@article{ author = "Karaman, Maja and Tesanovic, Kristina and Gorjanovic, Stanislava and Pastor, Ferenc and Simonovic, Mladen and Glumac, Miodrag and Pejin, Boris", year = "2021", abstract = "This study was focused on in vitro screening of the total antioxidant activity of the selected extracts of the mushroom Coprinus comatus and quinic acid, one of their antidiabetic ingredients, by an uncommon electrochemical assay. Indeed, direct current (DC) polarographic HydroxoPerhydroxo Mercury(II) Complex (HPMC) assay based on decrease of anodic limiting current originating from HPMC formation in alkaline solutions of hydrogen peroxide at potential of mercury dissolution, observed upon gradual addition of antioxidants, was applied herein for the estimation of the natural products' antioxidativity. Quinic acid was found to exhibit most promising antioxidant potential (4.0 ± 0.2%µL-1) being ≈ 2-fold more active than the screened C. comatus extract samples. Actually, such a finding puts some light on the antioxidativity of cyclic polyols, well understimated class of organic compounds, compared to aromatic (poly)phenolics. As a low cost, easy-to handle and accurate this polarographic assay may be thoroughly recommended for much broader use. [Formula: see text].", journal = "Natural Product Research", title = "Polarography as a technique of choice for the evaluation of total antioxidant activity: The case study of selected Coprinus Comatus extracts and quinic acid, their antidiabetic ingredient", volume = "35", number = "10", pages = "1711-1716", doi = "10.1080/14786419.2019.1628753" }
Karaman, M., Tesanovic, K., Gorjanovic, S., Pastor, F., Simonovic, M., Glumac, M.,& Pejin, B.. (2021). Polarography as a technique of choice for the evaluation of total antioxidant activity: The case study of selected Coprinus Comatus extracts and quinic acid, their antidiabetic ingredient. in Natural Product Research, 35(10), 1711-1716. https://doi.org/10.1080/14786419.2019.1628753
Karaman M, Tesanovic K, Gorjanovic S, Pastor F, Simonovic M, Glumac M, Pejin B. Polarography as a technique of choice for the evaluation of total antioxidant activity: The case study of selected Coprinus Comatus extracts and quinic acid, their antidiabetic ingredient. in Natural Product Research. 2021;35(10):1711-1716. doi:10.1080/14786419.2019.1628753 .
Karaman, Maja, Tesanovic, Kristina, Gorjanovic, Stanislava, Pastor, Ferenc, Simonovic, Mladen, Glumac, Miodrag, Pejin, Boris, "Polarography as a technique of choice for the evaluation of total antioxidant activity: The case study of selected Coprinus Comatus extracts and quinic acid, their antidiabetic ingredient" in Natural Product Research, 35, no. 10 (2021):1711-1716, https://doi.org/10.1080/14786419.2019.1628753 . .