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dc.creatorKaraman, Maja
dc.creatorTesanovic, Kristina
dc.creatorGorjanovic, Stanislava
dc.creatorPastor, Ferenc
dc.creatorSimonovic, Mladen
dc.creatorGlumac, Miodrag
dc.creatorPejin, Boris
dc.date.accessioned2021-12-01T12:41:45Z
dc.date.available2021-12-01T12:41:45Z
dc.date.issued2021
dc.identifier.issn1478-6419
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/pubmed/31192702
dc.identifier.urihttp://cherry.chem.bg.ac.rs/handle/123456789/4773
dc.description.abstractThis study was focused on in vitro screening of the total antioxidant activity of the selected extracts of the mushroom Coprinus comatus and quinic acid, one of their antidiabetic ingredients, by an uncommon electrochemical assay. Indeed, direct current (DC) polarographic HydroxoPerhydroxo Mercury(II) Complex (HPMC) assay based on decrease of anodic limiting current originating from HPMC formation in alkaline solutions of hydrogen peroxide at potential of mercury dissolution, observed upon gradual addition of antioxidants, was applied herein for the estimation of the natural products' antioxidativity. Quinic acid was found to exhibit most promising antioxidant potential (4.0 ± 0.2%µL-1) being ≈ 2-fold more active than the screened C. comatus extract samples. Actually, such a finding puts some light on the antioxidativity of cyclic polyols, well understimated class of organic compounds, compared to aromatic (poly)phenolics. As a low cost, easy-to handle and accurate this polarographic assay may be thoroughly recommended for much broader use. [Formula: see text].
dc.languageeng
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172053/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172058/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173040/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/43002/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/43010/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/46001/RS//
dc.rightsrestrictedAccess
dc.sourceNatural Product Research
dc.subjectAntioxidants
dc.subjectantioxidativity
dc.subjectBiological Products
dc.subjectCoprinus
dc.subjectcyclic polyols
dc.subjectHPMC assay
dc.subjectHypoglycemic Agents
dc.subjectMycelium
dc.subjectpolarography
dc.subjectPolarography
dc.subjectquinic acid
dc.subjectQuinic Acid
dc.titlePolarography as a technique of choice for the evaluation of total antioxidant activity: The case study of selected Coprinus Comatus extracts and quinic acid, their antidiabetic ingredient
dc.typearticleen
dc.rights.licenseARR
dc.citation.volume35
dc.citation.issue10
dc.citation.spage1711
dc.citation.epage1716
dc.identifier.wos000472327300001
dc.identifier.doi10.1080/14786419.2019.1628753
dc.citation.rankM22~
dc.type.versionpublishedVersion
dc.identifier.scopus2-s2.0-85067613887


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