Hieracium waldsteinii (Asteraceae) and Onosma stellulata (Boraginaceae) as a Source of Antioxidant and Antimicrobial Agents
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2022
Authors
Kostić, Aleksandar Ž.
Mačukanović-Jocić, Marina P.
Milinčić, Danijel D.

Petrović, Jovana D.
Gašić, Uroš M.

Gligorijević, Nevenka N.
Jarić, Snežana V.
Soković, Marina

Tešić, Živoslav Lj.

Pešić, Mirjana B.

Article (Published version)

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The current study aimed to phytochemically characterize (including a detailed phenolic profile) two endemic Balkan's species (Hieracium waldsteinii and Onosma stellulata) and determine their possible application as a source of natural antioxidant and antimicrobial agents. The main phenolic compound in both species (in all examined parts) was chlorogenic acid. Eriodictyol, genistein and naringenin were quantified only in H. waldsteinii while isorhamnetin-3-O-rutinoside and sinapic acid were characteristic for O. stellulata. The highest antioxidant activity (98 mg AAE/g dry weight for TAC assay) was ascribed to the flower extract of H. waldsteinii while the lowest results (∼4.3 mg AAE/g dry weight for FRP assay) were exhibited by the extracts obtained from the plant's stem. Antimicrobial assays showed moderate antibacterial, i. e., moderate/strong activity against several tested fungi (in particular Trichoderma viride). Correlation analysis revealed strong positive connection between phe...nolic compounds and reducing power of extracts as well as between total phenolic and flavonoid content and the obtained minimal inhibitory concentration recorded in antibacterial assays.
Keywords:
Anti-Bacterial Agents / antimicrobial activity / antioxidant properties / Antioxidants / Asteraceae / Boraginaceae / Hieracium waldsteinii / Onosma stellulata / phenolic composition / Phenols / Plant ExtractsSource:
Chemistry and Biodiversity, 2022, 19, 4, e202200069-Publisher:
- Wiley
Funding / projects:
- Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 200116 (University of Belgrade, Faculty of Agriculture) (RS-200116)
- Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 200007 (University of Belgrade, Institute for Biological Research 'Siniša Stanković') (RS-200007)
- Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 200043 (Institute of Oncology and Radiology of Serbia, Belgrade) (RS-200043)
DOI: 10.1002/cbdv.202200069
ISSN: 1612-1872
WoS: 000768882100001
Scopus: 2-s2.0-85126216260
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Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Kostić, Aleksandar Ž. AU - Mačukanović-Jocić, Marina P. AU - Milinčić, Danijel D. AU - Petrović, Jovana D. AU - Gašić, Uroš M. AU - Gligorijević, Nevenka N. AU - Jarić, Snežana V. AU - Soković, Marina AU - Tešić, Živoslav Lj. AU - Pešić, Mirjana B. PY - 2022 UR - http://www.ncbi.nlm.nih.gov/pubmed/35213785 UR - http://cherry.chem.bg.ac.rs/handle/123456789/5203 AB - The current study aimed to phytochemically characterize (including a detailed phenolic profile) two endemic Balkan's species (Hieracium waldsteinii and Onosma stellulata) and determine their possible application as a source of natural antioxidant and antimicrobial agents. The main phenolic compound in both species (in all examined parts) was chlorogenic acid. Eriodictyol, genistein and naringenin were quantified only in H. waldsteinii while isorhamnetin-3-O-rutinoside and sinapic acid were characteristic for O. stellulata. The highest antioxidant activity (98 mg AAE/g dry weight for TAC assay) was ascribed to the flower extract of H. waldsteinii while the lowest results (∼4.3 mg AAE/g dry weight for FRP assay) were exhibited by the extracts obtained from the plant's stem. Antimicrobial assays showed moderate antibacterial, i. e., moderate/strong activity against several tested fungi (in particular Trichoderma viride). Correlation analysis revealed strong positive connection between phenolic compounds and reducing power of extracts as well as between total phenolic and flavonoid content and the obtained minimal inhibitory concentration recorded in antibacterial assays. PB - Wiley T2 - Chemistry and Biodiversity T1 - Hieracium waldsteinii (Asteraceae) and Onosma stellulata (Boraginaceae) as a Source of Antioxidant and Antimicrobial Agents VL - 19 IS - 4 SP - e202200069 DO - 10.1002/cbdv.202200069 ER -
@article{ author = "Kostić, Aleksandar Ž. and Mačukanović-Jocić, Marina P. and Milinčić, Danijel D. and Petrović, Jovana D. and Gašić, Uroš M. and Gligorijević, Nevenka N. and Jarić, Snežana V. and Soković, Marina and Tešić, Živoslav Lj. and Pešić, Mirjana B.", year = "2022", abstract = "The current study aimed to phytochemically characterize (including a detailed phenolic profile) two endemic Balkan's species (Hieracium waldsteinii and Onosma stellulata) and determine their possible application as a source of natural antioxidant and antimicrobial agents. The main phenolic compound in both species (in all examined parts) was chlorogenic acid. Eriodictyol, genistein and naringenin were quantified only in H. waldsteinii while isorhamnetin-3-O-rutinoside and sinapic acid were characteristic for O. stellulata. The highest antioxidant activity (98 mg AAE/g dry weight for TAC assay) was ascribed to the flower extract of H. waldsteinii while the lowest results (∼4.3 mg AAE/g dry weight for FRP assay) were exhibited by the extracts obtained from the plant's stem. Antimicrobial assays showed moderate antibacterial, i. e., moderate/strong activity against several tested fungi (in particular Trichoderma viride). Correlation analysis revealed strong positive connection between phenolic compounds and reducing power of extracts as well as between total phenolic and flavonoid content and the obtained minimal inhibitory concentration recorded in antibacterial assays.", publisher = "Wiley", journal = "Chemistry and Biodiversity", title = "Hieracium waldsteinii (Asteraceae) and Onosma stellulata (Boraginaceae) as a Source of Antioxidant and Antimicrobial Agents", volume = "19", number = "4", pages = "e202200069", doi = "10.1002/cbdv.202200069" }
Kostić, A. Ž., Mačukanović-Jocić, M. P., Milinčić, D. D., Petrović, J. D., Gašić, U. M., Gligorijević, N. N., Jarić, S. V., Soković, M., Tešić, Ž. Lj.,& Pešić, M. B.. (2022). Hieracium waldsteinii (Asteraceae) and Onosma stellulata (Boraginaceae) as a Source of Antioxidant and Antimicrobial Agents. in Chemistry and Biodiversity Wiley., 19(4), e202200069. https://doi.org/10.1002/cbdv.202200069
Kostić AŽ, Mačukanović-Jocić MP, Milinčić DD, Petrović JD, Gašić UM, Gligorijević NN, Jarić SV, Soković M, Tešić ŽL, Pešić MB. Hieracium waldsteinii (Asteraceae) and Onosma stellulata (Boraginaceae) as a Source of Antioxidant and Antimicrobial Agents. in Chemistry and Biodiversity. 2022;19(4):e202200069. doi:10.1002/cbdv.202200069 .
Kostić, Aleksandar Ž., Mačukanović-Jocić, Marina P., Milinčić, Danijel D., Petrović, Jovana D., Gašić, Uroš M., Gligorijević, Nevenka N., Jarić, Snežana V., Soković, Marina, Tešić, Živoslav Lj., Pešić, Mirjana B., "Hieracium waldsteinii (Asteraceae) and Onosma stellulata (Boraginaceae) as a Source of Antioxidant and Antimicrobial Agents" in Chemistry and Biodiversity, 19, no. 4 (2022):e202200069, https://doi.org/10.1002/cbdv.202200069 . .