Faculty of Chemistry Repository - Cherry
University of Belgrade - Faculty of Chemistry
    • English
    • Српски
    • Српски (Serbia)
  • English 
    • English
    • Serbian (Cyrillic)
    • Serbian (Latin)
  • Login
View Item 
  •   Cherry
  • Hemijski fakultet
  • Publikacije
  • View Item
  •   Cherry
  • Hemijski fakultet
  • Publikacije
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Synthesis and biological activity of Pd(II) and Cu(II) complexes with acylhydrazones of usnic acid

No Thumbnail
Authors
Natić, Maja
Tešić, Živoslav Lj.
Anđelković, Katarina K.
Brčeski, Ilija
Radulović, Siniša
Manic, S
Sladić, Dušan
Article (Published version)
Metadata
Show full item record
Abstract
The complexes of Pd(II) and Cu(II) with the condensation products of usnic acid with hydrazides were prepared and characterized by elemental analyses, IR, H-1 NMR, and C-13 NMR spectroscopy. In all cases, the complexes appear to be monomeric and square-planar, with three binding sites occupied by the dianionic tridentate ligand, and the fourth position occupied by ethanol. The complexes were tested for in vitro growth inhibitory activity against Aspergillus niger, Escherichia coli, Pseudomonas aeruginosa, and Bacillus subtilis and were found to possess significant activity. The cytotoxic tests were carried out by utilization of the MTT (3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide) microculture colorimetric assay in which human cervix carcinoma HeLa cells were treated by continuous exposure (48 h) to the test agents. All investigated compounds showed cytotoxic activity against HeLa cells with IC50 values between 1.8 and 86.0 muM.
Keywords:
usnic acid / Pd(II) complex / Cu(II) complex / biological activity / synthesis
Source:
Synthesis and Reactivity in Inorganic and Metal-organic Chemistry, 2004, 34, 1, 101-113
Publisher:
  • Marcel Dekker Inc, New York

DOI: 10.1081/SIM-120027320

ISSN: 0094-5714

WoS: 000189254200007

Scopus: 2-s2.0-1642396487
[ Google Scholar ]
14
14
URI
https://cherry.chem.bg.ac.rs/handle/123456789/571
Collections
  • Publikacije
Institution/Community
Hemijski fakultet
TY  - JOUR
AU  - Natić, Maja
AU  - Tešić, Živoslav Lj.
AU  - Anđelković, Katarina K.
AU  - Brčeski, Ilija
AU  - Radulović, Siniša
AU  - Manic, S
AU  - Sladić, Dušan
PY  - 2004
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/571
AB  - The complexes of Pd(II) and Cu(II) with the condensation products of usnic acid with hydrazides were prepared and characterized by elemental analyses, IR, H-1 NMR, and C-13 NMR spectroscopy. In all cases, the complexes appear to be monomeric and square-planar, with three binding sites occupied by the dianionic tridentate ligand, and the fourth position occupied by ethanol. The complexes were tested for in vitro growth inhibitory activity against Aspergillus niger, Escherichia coli, Pseudomonas aeruginosa, and Bacillus subtilis and were found to possess significant activity. The cytotoxic tests were carried out by utilization of the MTT (3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide) microculture colorimetric assay in which human cervix carcinoma HeLa cells were treated by continuous exposure (48 h) to the test agents. All investigated compounds showed cytotoxic activity against HeLa cells with IC50 values between 1.8 and 86.0 muM.
PB  - Marcel Dekker Inc, New York
T2  - Synthesis and Reactivity in Inorganic and Metal-organic Chemistry
T1  - Synthesis and biological activity of Pd(II) and Cu(II) complexes with acylhydrazones of usnic acid
VL  - 34
IS  - 1
SP  - 101
EP  - 113
DO  - 10.1081/SIM-120027320
UR  - Kon_1570
ER  - 
@article{
author = "Natić, Maja and Tešić, Živoslav Lj. and Anđelković, Katarina K. and Brčeski, Ilija and Radulović, Siniša and Manic, S and Sladić, Dušan",
year = "2004",
abstract = "The complexes of Pd(II) and Cu(II) with the condensation products of usnic acid with hydrazides were prepared and characterized by elemental analyses, IR, H-1 NMR, and C-13 NMR spectroscopy. In all cases, the complexes appear to be monomeric and square-planar, with three binding sites occupied by the dianionic tridentate ligand, and the fourth position occupied by ethanol. The complexes were tested for in vitro growth inhibitory activity against Aspergillus niger, Escherichia coli, Pseudomonas aeruginosa, and Bacillus subtilis and were found to possess significant activity. The cytotoxic tests were carried out by utilization of the MTT (3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide) microculture colorimetric assay in which human cervix carcinoma HeLa cells were treated by continuous exposure (48 h) to the test agents. All investigated compounds showed cytotoxic activity against HeLa cells with IC50 values between 1.8 and 86.0 muM.",
publisher = "Marcel Dekker Inc, New York",
journal = "Synthesis and Reactivity in Inorganic and Metal-organic Chemistry",
title = "Synthesis and biological activity of Pd(II) and Cu(II) complexes with acylhydrazones of usnic acid",
volume = "34",
number = "1",
pages = "101-113",
doi = "10.1081/SIM-120027320",
url = "Kon_1570"
}
Natić, M., Tešić, Ž. Lj., Anđelković, K. K., Brčeski, I., Radulović, S., Manic, S.,& Sladić, D.. (2004). Synthesis and biological activity of Pd(II) and Cu(II) complexes with acylhydrazones of usnic acid. in Synthesis and Reactivity in Inorganic and Metal-organic Chemistry
Marcel Dekker Inc, New York., 34(1), 101-113.
https://doi.org/10.1081/SIM-120027320
Kon_1570
Natić M, Tešić ŽL, Anđelković KK, Brčeski I, Radulović S, Manic S, Sladić D. Synthesis and biological activity of Pd(II) and Cu(II) complexes with acylhydrazones of usnic acid. in Synthesis and Reactivity in Inorganic and Metal-organic Chemistry. 2004;34(1):101-113.
doi:10.1081/SIM-120027320
Kon_1570 .
Natić, Maja, Tešić, Živoslav Lj., Anđelković, Katarina K., Brčeski, Ilija, Radulović, Siniša, Manic, S, Sladić, Dušan, "Synthesis and biological activity of Pd(II) and Cu(II) complexes with acylhydrazones of usnic acid" in Synthesis and Reactivity in Inorganic and Metal-organic Chemistry, 34, no. 1 (2004):101-113,
https://doi.org/10.1081/SIM-120027320 .,
Kon_1570 .

DSpace software copyright © 2002-2015  DuraSpace
About CHERRY - CHEmistry RepositoRY | Send Feedback

re3dataOpenAIRERCUB
 

 

All of DSpaceInstitutions/communitiesAuthorsTitlesSubjectsThis institutionAuthorsTitlesSubjects

Statistics

View Usage Statistics

DSpace software copyright © 2002-2015  DuraSpace
About CHERRY - CHEmistry RepositoRY | Send Feedback

re3dataOpenAIRERCUB