Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction
Authors
Zeković, Zoran P.Smyatskaya, Yulia A.
Bazarnova, Julia G.
Pastor, Ferenc

Gorjanović, Stanislava

Gašić, Uroš M.

Pezo, Lato

Đurović, Saša

Article (Published version)
Metadata
Show full item recordAbstract
Stinging nettle (Urtica dioica L.) is one fantastic plant widely used in folk medicine, pharmacy, cosmetics, and food. This plant’s popularity may be explained by its chemical composition, containing a wide range of compounds significant for human health and diet. This study aimed to investigate extracts of exhausted stinging nettle leaves after supercritical fluid extraction obtained using ultrasound and microwave techniques. Extracts were analyzed to obtain insight into the chemical composition and biological activity. These extracts were shown to be more potent than those of previously untreated leaves. The principal component analysis was applied as a pattern recognition tool to visualize the antioxidant capacity and cytotoxic activity of extract obtained from exhausted stinging nettle leaves. An artificial neural network model is presented for the prediction of the antioxidant activity of samples according to polyphenolic profile data, showing a suitable anticipation property (the... r2 value during the training cycle for output variables was 0.999).
Keywords:
ANN modeling / biological activity / polyphenolic profile / HPLC-DAD-MS/MS / exhausted plant material / stinging nettle leavesSource:
Foods, 2023, 12, 4, 809-Publisher:
- MDPI
Funding / projects:
Collections
Institution/Community
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Zeković, Zoran P. AU - Smyatskaya, Yulia A. AU - Bazarnova, Julia G. AU - Pastor, Ferenc AU - Gorjanović, Stanislava AU - Gašić, Uroš M. AU - Pezo, Lato AU - Đurović, Saša PY - 2023 UR - http://cherry.chem.bg.ac.rs/handle/123456789/5886 AB - Stinging nettle (Urtica dioica L.) is one fantastic plant widely used in folk medicine, pharmacy, cosmetics, and food. This plant’s popularity may be explained by its chemical composition, containing a wide range of compounds significant for human health and diet. This study aimed to investigate extracts of exhausted stinging nettle leaves after supercritical fluid extraction obtained using ultrasound and microwave techniques. Extracts were analyzed to obtain insight into the chemical composition and biological activity. These extracts were shown to be more potent than those of previously untreated leaves. The principal component analysis was applied as a pattern recognition tool to visualize the antioxidant capacity and cytotoxic activity of extract obtained from exhausted stinging nettle leaves. An artificial neural network model is presented for the prediction of the antioxidant activity of samples according to polyphenolic profile data, showing a suitable anticipation property (the r2 value during the training cycle for output variables was 0.999). PB - MDPI T2 - Foods T1 - Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction VL - 12 IS - 4 SP - 809 DO - 10.3390/foods12040809 ER -
@article{ author = "Zeković, Zoran P. and Smyatskaya, Yulia A. and Bazarnova, Julia G. and Pastor, Ferenc and Gorjanović, Stanislava and Gašić, Uroš M. and Pezo, Lato and Đurović, Saša", year = "2023", abstract = "Stinging nettle (Urtica dioica L.) is one fantastic plant widely used in folk medicine, pharmacy, cosmetics, and food. This plant’s popularity may be explained by its chemical composition, containing a wide range of compounds significant for human health and diet. This study aimed to investigate extracts of exhausted stinging nettle leaves after supercritical fluid extraction obtained using ultrasound and microwave techniques. Extracts were analyzed to obtain insight into the chemical composition and biological activity. These extracts were shown to be more potent than those of previously untreated leaves. The principal component analysis was applied as a pattern recognition tool to visualize the antioxidant capacity and cytotoxic activity of extract obtained from exhausted stinging nettle leaves. An artificial neural network model is presented for the prediction of the antioxidant activity of samples according to polyphenolic profile data, showing a suitable anticipation property (the r2 value during the training cycle for output variables was 0.999).", publisher = "MDPI", journal = "Foods", title = "Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction", volume = "12", number = "4", pages = "809", doi = "10.3390/foods12040809" }
Zeković, Z. P., Smyatskaya, Y. A., Bazarnova, J. G., Pastor, F., Gorjanović, S., Gašić, U. M., Pezo, L.,& Đurović, S.. (2023). Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction. in Foods MDPI., 12(4), 809. https://doi.org/10.3390/foods12040809
Zeković ZP, Smyatskaya YA, Bazarnova JG, Pastor F, Gorjanović S, Gašić UM, Pezo L, Đurović S. Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction. in Foods. 2023;12(4):809. doi:10.3390/foods12040809 .
Zeković, Zoran P., Smyatskaya, Yulia A., Bazarnova, Julia G., Pastor, Ferenc, Gorjanović, Stanislava, Gašić, Uroš M., Pezo, Lato, Đurović, Saša, "Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction" in Foods, 12, no. 4 (2023):809, https://doi.org/10.3390/foods12040809 . .