Synthesis and crystal structure of the complex Ni(II) with 2-(2-(pyridin-2-ylmethylene)hydrazinyl-4-(4-tolyl)-1,3-thiazole

Abstract

Sintetisan je novi kompleks nikla(II) sa ligandom 2-(2(piridin-2-ilmetilen)hidrazinil)-4-(4-tolil)-1,3-tiazolom (HL) sa ciljem ispitivanja biološke aktivnosti i razumevanja načina koordinacije ovog tipa ligandnih sistema. Kompleks je sintetisan direktnom reakcijom HL sa Ni(CH3COO)2 × 4H2O, pri čemu je dobijen u obliku monokristala i struktura kompleksa rešena je primenom rendgenske strukturne analize. Kompleks [NiL2]·H2O ima distorgovanu oktaedarsku geometriju pri čemu su za Ni(II) koordinovana dva liganda u deprotonovanom obliku. Ligandi su koordinovani tridendatno preko piridinskog, iminskog i tiazolovog atoma azota, formirajući dva petočlana helatna prstena oko centralnog metalnog jona. Koordinovani ligandi nisu kristalografski ekvivalentni. U spoljašnjoj sferi kompleksa nalazi se jedan molekul kristalne vode. Kristalno pakovanje kompleksa zasnovano je na vodoničnim i π-π steking interakcijama. Merenjem molarne provodljivosti utvrđeno da je kompleks neelektrolit, a magnetna merenja su pokazala da je kompleks paramagnetičan.

New Ni(II) complex with 2-(2-(pyridine-2-ylmethylene)hydrazinyl)-4-(4-tolyl)-1,3-thiazole (HL) ligand was syntesized with the aim of evaluation of biological activity and understanding the modes of coordination of this type of ligand systems. The complex was syntesized by the reaction of HL with Ni(CH3COO)2 × 4H2O. It was obtained as a single crystal and its structure was determined by X-ray diffraction analysis. The complex [NiL2]·H2O has distorted octahedral geometry with two deprotonated HL ligands which are tridentately coordinated via pydidine, imine and thiazole nitrogen atoms, forming two five-membered chelate ring around the central metal ion. The coordinated ligands are not crystallographicaly equivalent. In outher sphere of the complex there is a water molecule. Crystal packings of the complex is based on hydrogen interactions and the π-π stacking interactions. Molar conductivity measurements showed that the complex is non-electrolyte, while magnetic measurements showed that the complex is paramagnetic.