In this paper the first complexes of M(2+) ions (M(2+) = Zn(2+), Cd(2+) and Co(2+)) with N-benzyloxycarbonyl-S-phenylalaninato ligand (1-3) are described. The new complexes were characterized by means of elemental analysis, IR and UV-vis spectroscopy, molar conductivity measurements and (1)H, (13)C and (15)N NMR spectroscopy (1D and 2D). The Co(II) complex adopts an octahedral geometry, and the Zn(II) and Cd(II) complexes adopt a tetrahedral one. For the first time, the antimicrobial activity of N-benzyloxycarbonyl-S-phenylalaninato ligand (N-Boc-S-phe) and the complexes 1-3 was investigated against Gram-positive: Micrococcus luteus, Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis and Bacillus subtilis and Gram-negative bacteria: Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and two strains of the yeast Candida albicans. It was shown that the complexes were effective against most strains. The best activity was detected against the yeast C. alb...icans. (C) 2008 Elsevier Masson SAS. All rights reserved.
TY - JOUR
AU - Mitić, Dragana
AU - Milenković, Marina
AU - Milosavljević, Slobodan M.
AU - Gođevac, Dejan
AU - Miodragović, Zoran
AU - Anđelković, Katarina K.
AU - Miodragović Đenana U.
PY - 2009
UR - http://cherry.chem.bg.ac.rs/handle/123456789/624
AB - In this paper the first complexes of M(2+) ions (M(2+) = Zn(2+), Cd(2+) and Co(2+)) with N-benzyloxycarbonyl-S-phenylalaninato ligand (1-3) are described. The new complexes were characterized by means of elemental analysis, IR and UV-vis spectroscopy, molar conductivity measurements and (1)H, (13)C and (15)N NMR spectroscopy (1D and 2D). The Co(II) complex adopts an octahedral geometry, and the Zn(II) and Cd(II) complexes adopt a tetrahedral one. For the first time, the antimicrobial activity of N-benzyloxycarbonyl-S-phenylalaninato ligand (N-Boc-S-phe) and the complexes 1-3 was investigated against Gram-positive: Micrococcus luteus, Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis and Bacillus subtilis and Gram-negative bacteria: Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and two strains of the yeast Candida albicans. It was shown that the complexes were effective against most strains. The best activity was detected against the yeast C. albicans. (C) 2008 Elsevier Masson SAS. All rights reserved.
PB - Elsevier France-Editions Scientifiques Medicales Elsevier, Paris
T2 - European Journal of Medicinal Chemistry
T1 - Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine
VL - 44
IS - 4
SP - 1537
EP - 1544
DO - 10.1016/j.ejmech.2008.07.017
ER -
@article{
author = "Mitić, Dragana and Milenković, Marina and Milosavljević, Slobodan M. and Gođevac, Dejan and Miodragović, Zoran and Anđelković, Katarina K. and Miodragović Đenana U.",
year = "2009",
url = "http://cherry.chem.bg.ac.rs/handle/123456789/624",
abstract = "In this paper the first complexes of M(2+) ions (M(2+) = Zn(2+), Cd(2+) and Co(2+)) with N-benzyloxycarbonyl-S-phenylalaninato ligand (1-3) are described. The new complexes were characterized by means of elemental analysis, IR and UV-vis spectroscopy, molar conductivity measurements and (1)H, (13)C and (15)N NMR spectroscopy (1D and 2D). The Co(II) complex adopts an octahedral geometry, and the Zn(II) and Cd(II) complexes adopt a tetrahedral one. For the first time, the antimicrobial activity of N-benzyloxycarbonyl-S-phenylalaninato ligand (N-Boc-S-phe) and the complexes 1-3 was investigated against Gram-positive: Micrococcus luteus, Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis and Bacillus subtilis and Gram-negative bacteria: Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and two strains of the yeast Candida albicans. It was shown that the complexes were effective against most strains. The best activity was detected against the yeast C. albicans. (C) 2008 Elsevier Masson SAS. All rights reserved.",
publisher = "Elsevier France-Editions Scientifiques Medicales Elsevier, Paris",
journal = "European Journal of Medicinal Chemistry",
title = "Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine",
volume = "44",
number = "4",
pages = "1537-1544",
doi = "10.1016/j.ejmech.2008.07.017"
}
Mitić D, Milenković M, Milosavljević SM, Gođevac D, Miodragović Z, Anđelković KK, Miodragović Đenana U.. Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine. European Journal of Medicinal Chemistry. 2009;44(4):1537-1544
Mitić, D., Milenković, M., Milosavljević, S. M., Gođevac, D., Miodragović, Z., Anđelković, K. K.,& Miodragović Đenana U. (2009). Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine.
European Journal of Medicinal ChemistryElsevier France-Editions Scientifiques Medicales Elsevier, Paris., 44(4), 1537-1544.
https://doi.org/10.1016/j.ejmech.2008.07.017
Mitić Dragana, Milenković Marina, Milosavljević Slobodan M., Gođevac Dejan, Miodragović Zoran, Anđelković Katarina K., Miodragović Đenana U., "Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine" 44, no. 4 (2009):1537-1544,
https://doi.org/10.1016/j.ejmech.2008.07.017 .
