A method for the stereoselective homologation of alpha-amino acids into syn-alpha-hydroxy-beta-amino acids is described. based on the conversion of stereoisomeric cyanohydrins into trans-oxazolines. The synthetic potential of the method is illustrated in the enantioselective formal synthesis of Bestatin.
TY - JOUR
AU - Tasic, G
AU - Matović, Radomir
AU - Saičić, Radomir
PY - 2004
UR - https://cherry.chem.bg.ac.rs/handle/123456789/683
AB - A method for the stereoselective homologation of alpha-amino acids into syn-alpha-hydroxy-beta-amino acids is described. based on the conversion of stereoisomeric cyanohydrins into trans-oxazolines. The synthetic potential of the method is illustrated in the enantioselective formal synthesis of Bestatin.
PB - Serbian Chemical Soc, Belgrade
T2 - Journal of the Serbian Chemical Society
T1 - Stereoselective synthesis of alpha-hydroxy-beta-amino acids: the chiral pool approach
VL - 69
IS - 11
SP - 981
EP - 990
DO - 10.2298/JSC0411981T
UR - Kon_1636
ER -
@article{
author = "Tasic, G and Matović, Radomir and Saičić, Radomir",
year = "2004",
abstract = "A method for the stereoselective homologation of alpha-amino acids into syn-alpha-hydroxy-beta-amino acids is described. based on the conversion of stereoisomeric cyanohydrins into trans-oxazolines. The synthetic potential of the method is illustrated in the enantioselective formal synthesis of Bestatin.",
publisher = "Serbian Chemical Soc, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "Stereoselective synthesis of alpha-hydroxy-beta-amino acids: the chiral pool approach",
volume = "69",
number = "11",
pages = "981-990",
doi = "10.2298/JSC0411981T",
url = "Kon_1636"
}
Tasic, G., Matović, R.,& Saičić, R.. (2004). Stereoselective synthesis of alpha-hydroxy-beta-amino acids: the chiral pool approach. in Journal of the Serbian Chemical Society
Serbian Chemical Soc, Belgrade., 69(11), 981-990.
https://doi.org/10.2298/JSC0411981T
Kon_1636
Tasic G, Matović R, Saičić R. Stereoselective synthesis of alpha-hydroxy-beta-amino acids: the chiral pool approach. in Journal of the Serbian Chemical Society. 2004;69(11):981-990.
doi:10.2298/JSC0411981T
Kon_1636 .
Tasic, G, Matović, Radomir, Saičić, Radomir, "Stereoselective synthesis of alpha-hydroxy-beta-amino acids: the chiral pool approach" in Journal of the Serbian Chemical Society, 69, no. 11 (2004):981-990,
https://doi.org/10.2298/JSC0411981T .,
Kon_1636 .
