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Stereoselective synthesis of alpha-hydroxy-beta-amino acids: the chiral pool approach

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2004
681.pdf (148.5Kb)
Authors
Tasic, G
Matović, Radomir
Saičić, Radomir
Article (Published version)
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Abstract
A method for the stereoselective homologation of alpha-amino acids into syn-alpha-hydroxy-beta-amino acids is described. based on the conversion of stereoisomeric cyanohydrins into trans-oxazolines. The synthetic potential of the method is illustrated in the enantioselective formal synthesis of Bestatin.
Keywords:
amino acids / cyanohydrins / bestatin / AHPA / oxazoline
Source:
Journal of the Serbian Chemical Society, 2004, 69, 11, 981-990
Publisher:
  • Serbian Chemical Soc, Belgrade

DOI: 10.2298/JSC0411981T

ISSN: 0352-5139

WoS: 000226120300018

Scopus: 2-s2.0-24944448953
[ Google Scholar ]
8
8
URI
https://cherry.chem.bg.ac.rs/handle/123456789/683
Collections
  • Publikacije
Institution/Community
Hemijski fakultet
TY  - JOUR
AU  - Tasic, G
AU  - Matović, Radomir
AU  - Saičić, Radomir
PY  - 2004
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/683
AB  - A method for the stereoselective homologation of alpha-amino acids into syn-alpha-hydroxy-beta-amino acids is described. based on the conversion of stereoisomeric cyanohydrins into trans-oxazolines. The synthetic potential of the method is illustrated in the enantioselective formal synthesis of Bestatin.
PB  - Serbian Chemical Soc, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - Stereoselective synthesis of alpha-hydroxy-beta-amino acids: the chiral pool approach
VL  - 69
IS  - 11
SP  - 981
EP  - 990
DO  - 10.2298/JSC0411981T
UR  - Kon_1636
ER  - 
@article{
author = "Tasic, G and Matović, Radomir and Saičić, Radomir",
year = "2004",
abstract = "A method for the stereoselective homologation of alpha-amino acids into syn-alpha-hydroxy-beta-amino acids is described. based on the conversion of stereoisomeric cyanohydrins into trans-oxazolines. The synthetic potential of the method is illustrated in the enantioselective formal synthesis of Bestatin.",
publisher = "Serbian Chemical Soc, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "Stereoselective synthesis of alpha-hydroxy-beta-amino acids: the chiral pool approach",
volume = "69",
number = "11",
pages = "981-990",
doi = "10.2298/JSC0411981T",
url = "Kon_1636"
}
Tasic, G., Matović, R.,& Saičić, R.. (2004). Stereoselective synthesis of alpha-hydroxy-beta-amino acids: the chiral pool approach. in Journal of the Serbian Chemical Society
Serbian Chemical Soc, Belgrade., 69(11), 981-990.
https://doi.org/10.2298/JSC0411981T
Kon_1636
Tasic G, Matović R, Saičić R. Stereoselective synthesis of alpha-hydroxy-beta-amino acids: the chiral pool approach. in Journal of the Serbian Chemical Society. 2004;69(11):981-990.
doi:10.2298/JSC0411981T
Kon_1636 .
Tasic, G, Matović, Radomir, Saičić, Radomir, "Stereoselective synthesis of alpha-hydroxy-beta-amino acids: the chiral pool approach" in Journal of the Serbian Chemical Society, 69, no. 11 (2004):981-990,
https://doi.org/10.2298/JSC0411981T .,
Kon_1636 .

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