Biological activity of some cobalt(II) and molybdenum(VI) complexes: in vitro cytotoxicity
Abstract
Cytotoxicity and cell growth inhibition studies were\performed for five distinct cobalt(II) [CO2(acac)tpmc](CIO4)(3), [Co-2(dibzac)tpmc](CIO4)(3). [Co-2(hfac)tpmc](CIO4)(3). [Co-2(tmhd)tpmc](CIO4)(3), and [Co-2(ox)tpmc](CIO4)(2).3H(2)O and five molybdenum(VI) complexes, [MoO2(pipdtc)(2)]. [MoO2(morphdtc)(2)]. [MoO2(timdtc)(2)], [MoO2(pzdtc)(2)] and [MoO2(N-Mepzdtc)(2)]. The former were tested in two leukemia cell lines: chronic myelogenic leukemia (K562) and human promyelocytic cell line (U937). They showed to have relatively high toxicity in K562 cells and a relatively low cytotoxicity in U937 cells. as assessed by both MTT and Trypan Blue assays. The five molybdenum complexes were tested in human promyelotic U937 cell line and they showed to have high toxicity.
Source:
Bioinorganic Chemistry and Applications, 2004, 2, 3-4, 193-207Publisher:
- Hindawi Publishing Corporation, New York
DOI: 10.1155/S1565363304000123
ISSN: 1565-3633
PubMed: 18365076
WoS: 000226194200002
Scopus: 2-s2.0-33645573601
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Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Katsaros, N AU - Katsarou, M AU - Sovilj, Sofija P. AU - Babic-Samardzija, K AU - Mitić, Dragana PY - 2004 UR - https://cherry.chem.bg.ac.rs/handle/123456789/684 AB - Cytotoxicity and cell growth inhibition studies were\performed for five distinct cobalt(II) [CO2(acac)tpmc](CIO4)(3), [Co-2(dibzac)tpmc](CIO4)(3). [Co-2(hfac)tpmc](CIO4)(3). [Co-2(tmhd)tpmc](CIO4)(3), and [Co-2(ox)tpmc](CIO4)(2).3H(2)O and five molybdenum(VI) complexes, [MoO2(pipdtc)(2)]. [MoO2(morphdtc)(2)]. [MoO2(timdtc)(2)], [MoO2(pzdtc)(2)] and [MoO2(N-Mepzdtc)(2)]. The former were tested in two leukemia cell lines: chronic myelogenic leukemia (K562) and human promyelocytic cell line (U937). They showed to have relatively high toxicity in K562 cells and a relatively low cytotoxicity in U937 cells. as assessed by both MTT and Trypan Blue assays. The five molybdenum complexes were tested in human promyelotic U937 cell line and they showed to have high toxicity. PB - Hindawi Publishing Corporation, New York T2 - Bioinorganic Chemistry and Applications T1 - Biological activity of some cobalt(II) and molybdenum(VI) complexes: in vitro cytotoxicity VL - 2 IS - 3-4 SP - 193 EP - 207 DO - 10.1155/S1565363304000123 ER -
@article{ author = "Katsaros, N and Katsarou, M and Sovilj, Sofija P. and Babic-Samardzija, K and Mitić, Dragana", year = "2004", abstract = "Cytotoxicity and cell growth inhibition studies were\performed for five distinct cobalt(II) [CO2(acac)tpmc](CIO4)(3), [Co-2(dibzac)tpmc](CIO4)(3). [Co-2(hfac)tpmc](CIO4)(3). [Co-2(tmhd)tpmc](CIO4)(3), and [Co-2(ox)tpmc](CIO4)(2).3H(2)O and five molybdenum(VI) complexes, [MoO2(pipdtc)(2)]. [MoO2(morphdtc)(2)]. [MoO2(timdtc)(2)], [MoO2(pzdtc)(2)] and [MoO2(N-Mepzdtc)(2)]. The former were tested in two leukemia cell lines: chronic myelogenic leukemia (K562) and human promyelocytic cell line (U937). They showed to have relatively high toxicity in K562 cells and a relatively low cytotoxicity in U937 cells. as assessed by both MTT and Trypan Blue assays. The five molybdenum complexes were tested in human promyelotic U937 cell line and they showed to have high toxicity.", publisher = "Hindawi Publishing Corporation, New York", journal = "Bioinorganic Chemistry and Applications", title = "Biological activity of some cobalt(II) and molybdenum(VI) complexes: in vitro cytotoxicity", volume = "2", number = "3-4", pages = "193-207", doi = "10.1155/S1565363304000123" }
Katsaros, N., Katsarou, M., Sovilj, S. P., Babic-Samardzija, K.,& Mitić, D.. (2004). Biological activity of some cobalt(II) and molybdenum(VI) complexes: in vitro cytotoxicity. in Bioinorganic Chemistry and Applications Hindawi Publishing Corporation, New York., 2(3-4), 193-207. https://doi.org/10.1155/S1565363304000123
Katsaros N, Katsarou M, Sovilj SP, Babic-Samardzija K, Mitić D. Biological activity of some cobalt(II) and molybdenum(VI) complexes: in vitro cytotoxicity. in Bioinorganic Chemistry and Applications. 2004;2(3-4):193-207. doi:10.1155/S1565363304000123 .
Katsaros, N, Katsarou, M, Sovilj, Sofija P., Babic-Samardzija, K, Mitić, Dragana, "Biological activity of some cobalt(II) and molybdenum(VI) complexes: in vitro cytotoxicity" in Bioinorganic Chemistry and Applications, 2, no. 3-4 (2004):193-207, https://doi.org/10.1155/S1565363304000123 . .