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dc.creatorKaluderovic, GN
dc.creatorDinovic, VM
dc.creatorJuranic, ZD
dc.creatorStanojković, Tatjana
dc.creatorSabo, Tibor
dc.date.accessioned2018-11-22T00:08:01Z
dc.date.available2018-11-22T00:08:01Z
dc.date.issued2005
dc.identifier.issn0162-0134
dc.identifier.urihttp://cherry.chem.bg.ac.rs/handle/123456789/685
dc.description.abstractThis paper reports on syntheses and characterization of chlorotribromo(O,O-n-butyl-ethylenediamine-N,N'-di-3-propanoate)platinum(IV) [II], dichlorodiiodo(O,O-ii-butyl-ethylenediamine-N,N'-di-3-propanoate)platinum(IV) [III], and dichloro(O,O-n-butyl-ethylenediamine-N,N'-di-3-propanoate)platinum(II) [V] complexes, with the formulae [Pt(dbeddp)Br3Cl], [Pt(dbeddp)Cl2I2] and [Pt(dbeddp)Cl-2], respectively. The complexes were characterized by elemental analysis, infrared, H-1 and C-13 NMR spectroscopy and electrospray mass spectrometry. In the aim to assess the selectivity in the antitumor action of these complexes, as well, as tetrachloro(O,O-n-butyl-ethylenediamine-N,N'-di-3-propanoate)platinum(IV) [I] and tetrachloro(O,O-n-pentyl-ethylenediamine-N,N'-di-3-propanoate)platinum(IV) [IV], the antiproliferative action of these compounds was determined to human adenocarcinoma HeLa cells, to human myelogenous leukemia K562 cells and to normal immunocompetent cells, i.e., on human peripheral blood mononuclear PBMC cells. (C) 2004 Elsevier Inc. All rights reserved.en
dc.publisherElsevier Science Inc, New York
dc.rightsrestrictedAccess
dc.sourceJournal of Inorganic Biochemistry
dc.subjectplatinum(IV) complexesen
dc.subjectEddpen
dc.subjectneoplastic cellsen
dc.subjectPBMCen
dc.titleActivity of some platinum(II/IV) complexes with O,O-n-butyl-and O,O-n-pentyl-ethylenediamine-N,N '-di-3-propanoate and halogeno ligands against HeLa and K562 cell lines and human PBMCen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractСабо, Тибор; Диновиц, ВМ; Јураниц, ЗД; Калудеровиц, ГН; Станојковиц, ТП;
dc.citation.volume99
dc.citation.issue2
dc.citation.spage488
dc.citation.epage496
dc.identifier.wos000226392400015
dc.identifier.doi10.1016/j.jinorgbio.2004.10.025
dc.citation.other99(2): 488-496
dc.citation.rankM22
dc.identifier.pmid15621281
dc.type.versionpublishedVersionen
dc.identifier.scopus2-s2.0-11144318782
dc.identifier.rcubKon_1638


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