Nucleophilic functionalization of 2-alkylidene-4-oxothiazolidines at C(5)-position induced by formation of novel pyridinium salt
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The synthesis of unsubstituted pyridinium salt containing the 4-oxothiazolidine moiety bonded via C(5) to the N position of the pyridine nucleus is reported. The nucleophilic displacement of pyridine from pyridinium salt by the selected nucleophiles leads to the formation of new 5-substituted 4-oxothiazolidines in good yields.
Keywords:4-oxothiazolidine / methoxy group / neutral nucleophile / nucleophilic substitution / pyridinium salt
Source:Phosphorus Sulfur and Silicon and the Related Elements, 2005, 180, 5-6, 1411-1415
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