Faculty of Chemistry Repository - Cherry
University of Belgrade - Faculty of Chemistry
    • English
    • Српски
    • Српски (Serbia)
  • English 
    • English
    • Serbian (Cyrilic)
    • Serbian (Latin)
  • Login
View Item 
  •   Faculty of Chemistry Repository - Cherry
  • Hemijski fakultet
  • Publikacije
  • View Item
  •   Faculty of Chemistry Repository - Cherry
  • Hemijski fakultet
  • Publikacije
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Synthesis, biological evaluation, and modeling of a C,D-seco-taxoid

Authorized Users Only
2005
Authors
Ferjančić, Zorana
Matović, Radomir
Čeković, Živorad
Snyder, JP
Saičić, Radomir
Article (Published version)
Metadata
Show full item record
Abstract
A C,D-seco-paclitaxel derivative 12 was prepared and tested for biological activity. The key step in the synthesis was a free radical fragmentation of the bicyclic tertiary alcohol 7 under the conditions of the hypobromite reaction. The compound 12 showed no activity in the tubulin test. (c) 2005 Elsevier Ltd. All rights reserved.
Keywords:
taxane antitumor agents / radicals and radical reactions / medium sized rings / natural products / molecular modeling
Source:
Tetrahedron Letters, 2005, 46, 30, 5049-5052
Publisher:
  • Pergamon-Elsevier Science Ltd, Oxford

DOI: 10.1016/j.tetlet.2005.05.071

ISSN: 0040-4039

WoS: 000230362300027

Scopus: 2-s2.0-20544454057
[ Google Scholar ]
8
6
URI
http://cherry.chem.bg.ac.rs/handle/123456789/716
Collections
  • Publikacije
Institution
Hemijski fakultet

DSpace software copyright © 2002-2015  DuraSpace
About CHERRY - CHEmistry RepositoRY | Send Feedback

OpenAIRERCUB
 

 

All of DSpaceInstitutionsAuthorsTitlesSubjectsThis institutionAuthorsTitlesSubjects

Statistics

View Usage Statistics

DSpace software copyright © 2002-2015  DuraSpace
About CHERRY - CHEmistry RepositoRY | Send Feedback

OpenAIRERCUB