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Synthesis of novel polar derivatives of the antimalarial endoperoxides ascaridole and dihydroascaridole

Authorized Users Only
2007
Authors
Hatzakis, Emmanuel
Opsenica, Igor
Šolaja, Bogdan A.
Stratakis, Manolis
Article (Published version)
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Abstract
Novel polar derivatives of the antimalarial endoperoxide ascaridole were synthesized based on the zeolite NaY-promoted isomerization of perillyl and nopol derivatives to conjugated cyclohexadienes, followed by reaction with singlet oxygen. Several unsaturated endoperoxides were in situ reduced with diimide to form dihydroascaridole derivatives, as well.
Keywords:
isomerization / zeolites / singlet oxygen / endoperoxides / ascaridole
Source:
Arkivoc, 2007, 124-135
Publisher:
  • Arkat Usa Inc, Gainesville

ISSN: 1424-6376

WoS: 000249060000012

Scopus: 2-s2.0-33846237367
[ Google Scholar ]
18
17
URI
http://cherry.chem.bg.ac.rs/handle/123456789/861
Collections
  • Publikacije
Institution
Hemijski fakultet
TY  - JOUR
AU  - Hatzakis, Emmanuel
AU  - Opsenica, Igor
AU  - Šolaja, Bogdan A.
AU  - Stratakis, Manolis
PY  - 2007
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/861
AB  - Novel polar derivatives of the antimalarial endoperoxide ascaridole were synthesized based on the zeolite NaY-promoted isomerization of perillyl and nopol derivatives to conjugated cyclohexadienes, followed by reaction with singlet oxygen. Several unsaturated endoperoxides were in situ reduced with diimide to form dihydroascaridole derivatives, as well.
PB  - Arkat Usa Inc, Gainesville
T2  - Arkivoc
T1  - Synthesis of novel polar derivatives of the antimalarial endoperoxides ascaridole and dihydroascaridole
SP  - 124
EP  - 135
ER  - 
@article{
author = "Hatzakis, Emmanuel and Opsenica, Igor and Šolaja, Bogdan A. and Stratakis, Manolis",
year = "2007",
url = "http://cherry.chem.bg.ac.rs/handle/123456789/861",
abstract = "Novel polar derivatives of the antimalarial endoperoxide ascaridole were synthesized based on the zeolite NaY-promoted isomerization of perillyl and nopol derivatives to conjugated cyclohexadienes, followed by reaction with singlet oxygen. Several unsaturated endoperoxides were in situ reduced with diimide to form dihydroascaridole derivatives, as well.",
publisher = "Arkat Usa Inc, Gainesville",
journal = "Arkivoc",
title = "Synthesis of novel polar derivatives of the antimalarial endoperoxides ascaridole and dihydroascaridole",
pages = "124-135"
}
Hatzakis E, Opsenica I, Šolaja BA, Stratakis M. Synthesis of novel polar derivatives of the antimalarial endoperoxides ascaridole and dihydroascaridole. Arkivoc. 2007;:124-135
Hatzakis, E., Opsenica, I., Šolaja, B. A.,& Stratakis, M. (2007). Synthesis of novel polar derivatives of the antimalarial endoperoxides ascaridole and dihydroascaridole.
ArkivocArkat Usa Inc, Gainesville., 124-135.
Hatzakis Emmanuel, Opsenica Igor, Šolaja Bogdan A., Stratakis Manolis, "Synthesis of novel polar derivatives of the antimalarial endoperoxides ascaridole and dihydroascaridole" (2007):124-135

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