Show simple item record

dc.creatorMicovic, Vuk
dc.creatorIvanović, Milovan
dc.creatorDošen-Mićović, Ljiljana
dc.date.accessioned2018-11-22T00:14:35Z
dc.date.available2018-11-22T00:14:35Z
dc.date.issued2009
dc.identifier.issn1610-2940
dc.identifier.urihttp://cherry.chem.bg.ac.rs/handle/123456789/872
dc.description.abstractAn automated docking procedure was used to study binding of a series of delta-selective ligands to three models of the delta-opioid receptor. These models are thought to represent the three ligand-specific receptor conformations. Docking results are in agreement with point mutation studies and suggest that different ligands-agonists and antagonists-may bind to the same binding site under different receptor conformations. Docking to different receptor models ( conformations) also suggests that by changing to a receptor-specific conformation, the receptor may open or close different binding sites to other ligands.en
dc.publisherSpringer, New York
dc.relationMinistry of Science and Environmental Protection of the Republic of Serbia
dc.rightsrestrictedAccess
dc.sourceJournal of Molecular Modeling
dc.subjectDelta opioid receptoren
dc.subjectDocking simulationen
dc.subjectLigand-receptor interactionsen
dc.subjectMolecular modelingen
dc.titleDocking studies suggest ligand-specific delta-opioid receptor conformationsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractМицовиц, Вук; Ивановић, Милован; Досен-Мицовиц, Љиљана;
dc.citation.volume15
dc.citation.issue3
dc.citation.spage267
dc.citation.epage280
dc.identifier.wos000262578200005
dc.identifier.doi10.1007/s00894-008-0396-7
dc.citation.other15(3): 267-280
dc.citation.rankM21
dc.identifier.pmid19052783
dc.type.versionpublishedVersionen
dc.identifier.scopus2-s2.0-59149102761
dc.identifier.rcubKon_1825


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record