Kinetic method for the determination of traces of thyroxine by its catalytic effect on the Mn(III) metaphosphate-As (III) reaction
Само за регистроване кориснике
2008
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
A new, highly sensitive and simple kinetic method for the determination of thyroxine was proposed. The method was based on the catalytic effect of thyroxine on the oxidation of As(III) by Mn(III) metaphosphate. The kinetics of the reaction was studied in the presence of orthophosphoric acid. The reaction rate was followed spectrophotometrically at 516 nm. It was established that orthophosphoric acid increased the reaction rate and that the extent of the non-catalytic reaction was extremely small. A kinetic equation was postulated and the apparent rate constant was calculated. The dependence of the reaction rate on temperature was investigated and the energy of activation and other kinetic parameters were determined. Thyroxine was determined under the optimal experimental conditions in the range 7.0 x 10(-9) to 3.0 x 10(-8) mol L-1 with a relative standard deviation up to 6.7% and a detection limit of 2.7 x 10(-9) mol L-1. In the presence of 0.08 mol L-1 chloride, the detection limit de...creased to 6.6 x 10(-10) mol L-1. The proposed method was applied for the determination of thyroxine in tablets. The accuracy of the method was evaluated by comparison with the HPLC method. (C) 2007 Elsevier B.V. All rights reserved.
Кључне речи:
thyroxine / kinetic catalytic determination of thyroxine / manganese(III) metaphosphate-arsenic(III) reaction in orthophosphoric acidИзвор:
Talanta, 2008, 74, 5, 1556-1561Издавач:
- Elsevier Science Bv, Amsterdam
Финансирање / пројекти:
- Проучавање односа реактивности, нековалентних интеракција и структуре молекула и моделовање хемијских система (RS-MESTD-MPN2006-2010-142037)
DOI: 10.1016/j.talanta.2007.09.033
ISSN: 0039-9140
PubMed: 18371817
WoS: 000253514700063
Scopus: 2-s2.0-38349145367
Колекције
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Pastor, Ferenc AU - Milovanović, Gordana A. AU - Todorović, Marija B. PY - 2008 UR - https://cherry.chem.bg.ac.rs/handle/123456789/918 AB - A new, highly sensitive and simple kinetic method for the determination of thyroxine was proposed. The method was based on the catalytic effect of thyroxine on the oxidation of As(III) by Mn(III) metaphosphate. The kinetics of the reaction was studied in the presence of orthophosphoric acid. The reaction rate was followed spectrophotometrically at 516 nm. It was established that orthophosphoric acid increased the reaction rate and that the extent of the non-catalytic reaction was extremely small. A kinetic equation was postulated and the apparent rate constant was calculated. The dependence of the reaction rate on temperature was investigated and the energy of activation and other kinetic parameters were determined. Thyroxine was determined under the optimal experimental conditions in the range 7.0 x 10(-9) to 3.0 x 10(-8) mol L-1 with a relative standard deviation up to 6.7% and a detection limit of 2.7 x 10(-9) mol L-1. In the presence of 0.08 mol L-1 chloride, the detection limit decreased to 6.6 x 10(-10) mol L-1. The proposed method was applied for the determination of thyroxine in tablets. The accuracy of the method was evaluated by comparison with the HPLC method. (C) 2007 Elsevier B.V. All rights reserved. PB - Elsevier Science Bv, Amsterdam T2 - Talanta T1 - Kinetic method for the determination of traces of thyroxine by its catalytic effect on the Mn(III) metaphosphate-As (III) reaction VL - 74 IS - 5 SP - 1556 EP - 1561 DO - 10.1016/j.talanta.2007.09.033 ER -
@article{ author = "Pastor, Ferenc and Milovanović, Gordana A. and Todorović, Marija B.", year = "2008", abstract = "A new, highly sensitive and simple kinetic method for the determination of thyroxine was proposed. The method was based on the catalytic effect of thyroxine on the oxidation of As(III) by Mn(III) metaphosphate. The kinetics of the reaction was studied in the presence of orthophosphoric acid. The reaction rate was followed spectrophotometrically at 516 nm. It was established that orthophosphoric acid increased the reaction rate and that the extent of the non-catalytic reaction was extremely small. A kinetic equation was postulated and the apparent rate constant was calculated. The dependence of the reaction rate on temperature was investigated and the energy of activation and other kinetic parameters were determined. Thyroxine was determined under the optimal experimental conditions in the range 7.0 x 10(-9) to 3.0 x 10(-8) mol L-1 with a relative standard deviation up to 6.7% and a detection limit of 2.7 x 10(-9) mol L-1. In the presence of 0.08 mol L-1 chloride, the detection limit decreased to 6.6 x 10(-10) mol L-1. The proposed method was applied for the determination of thyroxine in tablets. The accuracy of the method was evaluated by comparison with the HPLC method. (C) 2007 Elsevier B.V. All rights reserved.", publisher = "Elsevier Science Bv, Amsterdam", journal = "Talanta", title = "Kinetic method for the determination of traces of thyroxine by its catalytic effect on the Mn(III) metaphosphate-As (III) reaction", volume = "74", number = "5", pages = "1556-1561", doi = "10.1016/j.talanta.2007.09.033" }
Pastor, F., Milovanović, G. A.,& Todorović, M. B.. (2008). Kinetic method for the determination of traces of thyroxine by its catalytic effect on the Mn(III) metaphosphate-As (III) reaction. in Talanta Elsevier Science Bv, Amsterdam., 74(5), 1556-1561. https://doi.org/10.1016/j.talanta.2007.09.033
Pastor F, Milovanović GA, Todorović MB. Kinetic method for the determination of traces of thyroxine by its catalytic effect on the Mn(III) metaphosphate-As (III) reaction. in Talanta. 2008;74(5):1556-1561. doi:10.1016/j.talanta.2007.09.033 .
Pastor, Ferenc, Milovanović, Gordana A., Todorović, Marija B., "Kinetic method for the determination of traces of thyroxine by its catalytic effect on the Mn(III) metaphosphate-As (III) reaction" in Talanta, 74, no. 5 (2008):1556-1561, https://doi.org/10.1016/j.talanta.2007.09.033 . .