Hyperatomarin, an antibacterial prenylated phloroglucinol from Hypericum atomarium ssp degenii
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2003
Authors
Savikin-Fodulovic, KAljančić, Ivana
Vajs, Vlatka
Menkonic, N
Macura, S.
Gojgić-Cvijović, Gordana D.
Milosavljevic, S
Article (Published version)
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shown by quantitative H-1 NMR measurements, a lipophilic extract of the aerial parts of Hypericum atomarium ssp. degenii contained a high percentage (3.1% per weight of dried plant material) of a prenylated phloroglucinol (1). Compound 1, named hyperatomarin, occurring in two tautomeric forms (1a reversible arrow 1b), was isolated by bioactivity-guided preparative TLC and was identified on the basis of spectral data interpretation. This isolated phloroglucinol exhibited activity against Gram-positive (Staphyloccocus aureus and Microccocus luteus) and Gram-positive spore-forming bacteria (Bacillus subtilis and B. IP 5832).
Source:
Journal of Natural Products, 2003, 66, 9, 1236-1238Publisher:
- Amer Chemical Soc, Washington
DOI: 10.1021/np030131o
ISSN: 0163-3864
PubMed: 14510605
WoS: 000185609400020
Scopus: 2-s2.0-0141566417
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Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Savikin-Fodulovic, K AU - Aljančić, Ivana AU - Vajs, Vlatka AU - Menkonic, N AU - Macura, S. AU - Gojgić-Cvijović, Gordana D. AU - Milosavljevic, S PY - 2003 UR - https://cherry.chem.bg.ac.rs/handle/123456789/151 AB - shown by quantitative H-1 NMR measurements, a lipophilic extract of the aerial parts of Hypericum atomarium ssp. degenii contained a high percentage (3.1% per weight of dried plant material) of a prenylated phloroglucinol (1). Compound 1, named hyperatomarin, occurring in two tautomeric forms (1a reversible arrow 1b), was isolated by bioactivity-guided preparative TLC and was identified on the basis of spectral data interpretation. This isolated phloroglucinol exhibited activity against Gram-positive (Staphyloccocus aureus and Microccocus luteus) and Gram-positive spore-forming bacteria (Bacillus subtilis and B. IP 5832). PB - Amer Chemical Soc, Washington T2 - Journal of Natural Products T1 - Hyperatomarin, an antibacterial prenylated phloroglucinol from Hypericum atomarium ssp degenii VL - 66 IS - 9 SP - 1236 EP - 1238 DO - 10.1021/np030131o ER -
@article{ author = "Savikin-Fodulovic, K and Aljančić, Ivana and Vajs, Vlatka and Menkonic, N and Macura, S. and Gojgić-Cvijović, Gordana D. and Milosavljevic, S", year = "2003", abstract = "shown by quantitative H-1 NMR measurements, a lipophilic extract of the aerial parts of Hypericum atomarium ssp. degenii contained a high percentage (3.1% per weight of dried plant material) of a prenylated phloroglucinol (1). Compound 1, named hyperatomarin, occurring in two tautomeric forms (1a reversible arrow 1b), was isolated by bioactivity-guided preparative TLC and was identified on the basis of spectral data interpretation. This isolated phloroglucinol exhibited activity against Gram-positive (Staphyloccocus aureus and Microccocus luteus) and Gram-positive spore-forming bacteria (Bacillus subtilis and B. IP 5832).", publisher = "Amer Chemical Soc, Washington", journal = "Journal of Natural Products", title = "Hyperatomarin, an antibacterial prenylated phloroglucinol from Hypericum atomarium ssp degenii", volume = "66", number = "9", pages = "1236-1238", doi = "10.1021/np030131o" }
Savikin-Fodulovic, K., Aljančić, I., Vajs, V., Menkonic, N., Macura, S., Gojgić-Cvijović, G. D.,& Milosavljevic, S.. (2003). Hyperatomarin, an antibacterial prenylated phloroglucinol from Hypericum atomarium ssp degenii. in Journal of Natural Products Amer Chemical Soc, Washington., 66(9), 1236-1238. https://doi.org/10.1021/np030131o
Savikin-Fodulovic K, Aljančić I, Vajs V, Menkonic N, Macura S, Gojgić-Cvijović GD, Milosavljevic S. Hyperatomarin, an antibacterial prenylated phloroglucinol from Hypericum atomarium ssp degenii. in Journal of Natural Products. 2003;66(9):1236-1238. doi:10.1021/np030131o .
Savikin-Fodulovic, K, Aljančić, Ivana, Vajs, Vlatka, Menkonic, N, Macura, S., Gojgić-Cvijović, Gordana D., Milosavljevic, S, "Hyperatomarin, an antibacterial prenylated phloroglucinol from Hypericum atomarium ssp degenii" in Journal of Natural Products, 66, no. 9 (2003):1236-1238, https://doi.org/10.1021/np030131o . .