Assessment of non-steroidal anti-inflammatory and analgesic pharmaceuticals in seawaters of North of Portugal: Occurrence and environmental risk
Samo za registrovane korisnike
2015
Autori
Lolić, AleksandarPaiga, Paula
Santos, Lucia H. M. L. M.
Ramos, Sandra
Correia, Manuela
Delerue-Matos, Cristina
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
The occurrence of seven pharmaceuticals and two metabolites belonging to non-steroidal anti-inflammatory drugs and analgesics therapeutic classes was studied in seawaters. A total of 101 samples covering fourteen beaches and five cities were evaluated in order to assess the spatial distribution of pharmaceuticals among north Portuguese coast. Seawaters were selected in order to embrace different bathing water quality (excellent, good and sufficient). Acetaminophen, ketoprofen and the metabolite hydroxyibuprofen were detected in all the seawater samples at maximum concentrations of 584, 89.7 and 287 ng L-1, respectively. Carboxyibuprofen had the highest seawater concentration (1227 ng L-1). The temporal distribution of the selected pharmaceuticals during the bathing season showed that, in general, higher concentrations were detected in August and September. The environmental risk posed by the pharmaceuticals detected in seawaters towards different trophic levels (fish, daphnids and alga...e) was also assessed. Only diclofenac showed hazard quotients above one for fish, representing a potential risk for aquatic organisms. These results were observed in seawaters classified as excellent bathing water. Additional data is needed in order to support the identification and prioritization of risks posed by pharmaceuticals in marine environment.
Ključne reči:
Seawater / North of Portugal / Non-steroidal anti-inflammatory drugs / Analgesics / UHPLC-MS/MS / Environmental risk assessmentIzvor:
Science of the Total Environment, 2015, 508, 240-250Izdavač:
- Elsevier Science Bv, Amsterdam
Finansiranje / projekti:
- national funds through FCT - Foundation for Science and Technology [PEst-C/EQB/LA0006/2013, PEst-C/MAR/LA0015/2013]
- European Regional Development Fund (ERDF) through the COMPETE - Operational Competitiveness Programme
Napomena:
- Supplementary material: http://cherry.chem.bg.ac.rs/handle/123456789/3340
DOI: 10.1016/j.scitotenv.2014.11.097
ISSN: 0048-9697
PubMed: 25481252
WoS: 000349195100028
Scopus: 2-s2.0-84913557736
Kolekcije
Institucija/grupa
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Lolić, Aleksandar AU - Paiga, Paula AU - Santos, Lucia H. M. L. M. AU - Ramos, Sandra AU - Correia, Manuela AU - Delerue-Matos, Cristina PY - 2015 UR - https://cherry.chem.bg.ac.rs/handle/123456789/1653 AB - The occurrence of seven pharmaceuticals and two metabolites belonging to non-steroidal anti-inflammatory drugs and analgesics therapeutic classes was studied in seawaters. A total of 101 samples covering fourteen beaches and five cities were evaluated in order to assess the spatial distribution of pharmaceuticals among north Portuguese coast. Seawaters were selected in order to embrace different bathing water quality (excellent, good and sufficient). Acetaminophen, ketoprofen and the metabolite hydroxyibuprofen were detected in all the seawater samples at maximum concentrations of 584, 89.7 and 287 ng L-1, respectively. Carboxyibuprofen had the highest seawater concentration (1227 ng L-1). The temporal distribution of the selected pharmaceuticals during the bathing season showed that, in general, higher concentrations were detected in August and September. The environmental risk posed by the pharmaceuticals detected in seawaters towards different trophic levels (fish, daphnids and algae) was also assessed. Only diclofenac showed hazard quotients above one for fish, representing a potential risk for aquatic organisms. These results were observed in seawaters classified as excellent bathing water. Additional data is needed in order to support the identification and prioritization of risks posed by pharmaceuticals in marine environment. PB - Elsevier Science Bv, Amsterdam T2 - Science of the Total Environment T1 - Assessment of non-steroidal anti-inflammatory and analgesic pharmaceuticals in seawaters of North of Portugal: Occurrence and environmental risk VL - 508 SP - 240 EP - 250 DO - 10.1016/j.scitotenv.2014.11.097 ER -
@article{ author = "Lolić, Aleksandar and Paiga, Paula and Santos, Lucia H. M. L. M. and Ramos, Sandra and Correia, Manuela and Delerue-Matos, Cristina", year = "2015", abstract = "The occurrence of seven pharmaceuticals and two metabolites belonging to non-steroidal anti-inflammatory drugs and analgesics therapeutic classes was studied in seawaters. A total of 101 samples covering fourteen beaches and five cities were evaluated in order to assess the spatial distribution of pharmaceuticals among north Portuguese coast. Seawaters were selected in order to embrace different bathing water quality (excellent, good and sufficient). Acetaminophen, ketoprofen and the metabolite hydroxyibuprofen were detected in all the seawater samples at maximum concentrations of 584, 89.7 and 287 ng L-1, respectively. Carboxyibuprofen had the highest seawater concentration (1227 ng L-1). The temporal distribution of the selected pharmaceuticals during the bathing season showed that, in general, higher concentrations were detected in August and September. The environmental risk posed by the pharmaceuticals detected in seawaters towards different trophic levels (fish, daphnids and algae) was also assessed. Only diclofenac showed hazard quotients above one for fish, representing a potential risk for aquatic organisms. These results were observed in seawaters classified as excellent bathing water. Additional data is needed in order to support the identification and prioritization of risks posed by pharmaceuticals in marine environment.", publisher = "Elsevier Science Bv, Amsterdam", journal = "Science of the Total Environment", title = "Assessment of non-steroidal anti-inflammatory and analgesic pharmaceuticals in seawaters of North of Portugal: Occurrence and environmental risk", volume = "508", pages = "240-250", doi = "10.1016/j.scitotenv.2014.11.097" }
Lolić, A., Paiga, P., Santos, L. H. M. L. M., Ramos, S., Correia, M.,& Delerue-Matos, C.. (2015). Assessment of non-steroidal anti-inflammatory and analgesic pharmaceuticals in seawaters of North of Portugal: Occurrence and environmental risk. in Science of the Total Environment Elsevier Science Bv, Amsterdam., 508, 240-250. https://doi.org/10.1016/j.scitotenv.2014.11.097
Lolić A, Paiga P, Santos LHMLM, Ramos S, Correia M, Delerue-Matos C. Assessment of non-steroidal anti-inflammatory and analgesic pharmaceuticals in seawaters of North of Portugal: Occurrence and environmental risk. in Science of the Total Environment. 2015;508:240-250. doi:10.1016/j.scitotenv.2014.11.097 .
Lolić, Aleksandar, Paiga, Paula, Santos, Lucia H. M. L. M., Ramos, Sandra, Correia, Manuela, Delerue-Matos, Cristina, "Assessment of non-steroidal anti-inflammatory and analgesic pharmaceuticals in seawaters of North of Portugal: Occurrence and environmental risk" in Science of the Total Environment, 508 (2015):240-250, https://doi.org/10.1016/j.scitotenv.2014.11.097 . .