Properties and applications of undecylprodigiosin and other bacterial prodigiosins
Samo za registrovane korisnike
2014
Autori
Stanković, NadaŠenerović, Lidija
Ilić-Tomić, Tatjana
Vasiljević, Branka
Nikodinović-Runić, Jasmina
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
The growing demand to fulfill the needs of present-day medicine in terms of novel effective molecules has lead to reexamining some of the old and known bacterial secondary metabolites. Bacterial prodigiosins (prodiginines) have a long history of being re markable multipurpose compounds, best examined for their anticancer and antimalarial activities. Production of prodigiosin in the most common producer strain Serratia marcescens has been described in great detail. However, few reports have discussed the ecophysiological roles of these molecules in the producing strains, as well as their antibiotic and UV-protective properties. This review describes recent advances in the production process, biosynthesis, properties, and applications of bacterial prodigiosins. Special emphasis is put on undecylprodigiosin which has generally been a less studied member of the prodigiosin family. In addition, it has been suggested that proteins involved in undecylprodigiosin synthesis, RedG and RedH, coul...d be a useful addition to the biocatalytic toolbox being able to mediate regio- and stereoselective oxidative cyclization. Judging by the number of recent references (216 for the 2007-2013 period), it has become clear that undecylprodigiosin and other bacterial prodigiosins still hold surprises in terms of valuable properties and applicative potential to medical and other industrial fields and that they still deserve continuing research curiosity.
Ključne reči:
Bacterial pigment / Undecylprodigiosin / Prodigiosin / Biosynthesis / ApplicationIzvor:
Applied Microbiology and Biotechnology, 2014, 98, 9, 3841-3858Izdavač:
- Springer, New York
Finansiranje / projekti:
- Izučavanje mikrobiološkog diverziteta i karakterizacija korisnih sredinskih mikroorganizama (RS-MESTD-Basic Research (BR or ON)-173048)
DOI: 10.1007/s00253-014-5590-1
ISSN: 0175-7598
PubMed: 24562326
WoS: 000334433700001
Scopus: 2-s2.0-84899923115
Kolekcije
Institucija/grupa
Inovacioni centar / Innovation CentreTY - JOUR AU - Stanković, Nada AU - Šenerović, Lidija AU - Ilić-Tomić, Tatjana AU - Vasiljević, Branka AU - Nikodinović-Runić, Jasmina PY - 2014 UR - https://cherry.chem.bg.ac.rs/handle/123456789/1763 AB - The growing demand to fulfill the needs of present-day medicine in terms of novel effective molecules has lead to reexamining some of the old and known bacterial secondary metabolites. Bacterial prodigiosins (prodiginines) have a long history of being re markable multipurpose compounds, best examined for their anticancer and antimalarial activities. Production of prodigiosin in the most common producer strain Serratia marcescens has been described in great detail. However, few reports have discussed the ecophysiological roles of these molecules in the producing strains, as well as their antibiotic and UV-protective properties. This review describes recent advances in the production process, biosynthesis, properties, and applications of bacterial prodigiosins. Special emphasis is put on undecylprodigiosin which has generally been a less studied member of the prodigiosin family. In addition, it has been suggested that proteins involved in undecylprodigiosin synthesis, RedG and RedH, could be a useful addition to the biocatalytic toolbox being able to mediate regio- and stereoselective oxidative cyclization. Judging by the number of recent references (216 for the 2007-2013 period), it has become clear that undecylprodigiosin and other bacterial prodigiosins still hold surprises in terms of valuable properties and applicative potential to medical and other industrial fields and that they still deserve continuing research curiosity. PB - Springer, New York T2 - Applied Microbiology and Biotechnology T1 - Properties and applications of undecylprodigiosin and other bacterial prodigiosins VL - 98 IS - 9 SP - 3841 EP - 3858 DO - 10.1007/s00253-014-5590-1 ER -
@article{ author = "Stanković, Nada and Šenerović, Lidija and Ilić-Tomić, Tatjana and Vasiljević, Branka and Nikodinović-Runić, Jasmina", year = "2014", abstract = "The growing demand to fulfill the needs of present-day medicine in terms of novel effective molecules has lead to reexamining some of the old and known bacterial secondary metabolites. Bacterial prodigiosins (prodiginines) have a long history of being re markable multipurpose compounds, best examined for their anticancer and antimalarial activities. Production of prodigiosin in the most common producer strain Serratia marcescens has been described in great detail. However, few reports have discussed the ecophysiological roles of these molecules in the producing strains, as well as their antibiotic and UV-protective properties. This review describes recent advances in the production process, biosynthesis, properties, and applications of bacterial prodigiosins. Special emphasis is put on undecylprodigiosin which has generally been a less studied member of the prodigiosin family. In addition, it has been suggested that proteins involved in undecylprodigiosin synthesis, RedG and RedH, could be a useful addition to the biocatalytic toolbox being able to mediate regio- and stereoselective oxidative cyclization. Judging by the number of recent references (216 for the 2007-2013 period), it has become clear that undecylprodigiosin and other bacterial prodigiosins still hold surprises in terms of valuable properties and applicative potential to medical and other industrial fields and that they still deserve continuing research curiosity.", publisher = "Springer, New York", journal = "Applied Microbiology and Biotechnology", title = "Properties and applications of undecylprodigiosin and other bacterial prodigiosins", volume = "98", number = "9", pages = "3841-3858", doi = "10.1007/s00253-014-5590-1" }
Stanković, N., Šenerović, L., Ilić-Tomić, T., Vasiljević, B.,& Nikodinović-Runić, J.. (2014). Properties and applications of undecylprodigiosin and other bacterial prodigiosins. in Applied Microbiology and Biotechnology Springer, New York., 98(9), 3841-3858. https://doi.org/10.1007/s00253-014-5590-1
Stanković N, Šenerović L, Ilić-Tomić T, Vasiljević B, Nikodinović-Runić J. Properties and applications of undecylprodigiosin and other bacterial prodigiosins. in Applied Microbiology and Biotechnology. 2014;98(9):3841-3858. doi:10.1007/s00253-014-5590-1 .
Stanković, Nada, Šenerović, Lidija, Ilić-Tomić, Tatjana, Vasiljević, Branka, Nikodinović-Runić, Jasmina, "Properties and applications of undecylprodigiosin and other bacterial prodigiosins" in Applied Microbiology and Biotechnology, 98, no. 9 (2014):3841-3858, https://doi.org/10.1007/s00253-014-5590-1 . .