Biological activity of two isomeric N-heteroaromatic selenosemicarbazones and their metal complexes
Samo za registrovane korisnike
2014
Autori
Filipović, Nenad R.Polović, Natalija
Rašković, Brankica
Misirlić-Denčić, Sonja
Dulović, Marija
Savić, Milena
Nikšić, Miomir
Mitić, Dragana
Anđelković, Katarina K.
Todorović, Tamara
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
New square-planar Pd(II) and Pt(II) complexes with 8-quinolinecarboxaldehyde selenosemicarbazone have been synthesized and characterized by use of elemental analysis, molar conductivity measurements, and IR and NMR spectroscopy. The cytotoxic activity of the ligand, new Pt(II) and Pd(II) compounds, and previously synthesized Pd(II), Pt(II), Cd(II), and Ni(II) complexes with the analogous ligand, 2-quinolinecarboxaldehyde selenosemicarbazone, was tested against two human cancer cell lines: lung carcinoma (H460) and glioma (U251). The potential of these compounds to induce perturbations of the H460 cell cycle was also evaluated. These substances had an excellent radical-scavenging effect against ABTS radical cations. The best antimicrobial activity, among two yeasts and eight bacterial strains tested, was against Bacillus cereus.
Ključne reči:
Antimicrobial activity / Antioxidants / Cytotoxicity / Coordination chemistry / Schiff basesIzvor:
Monatshefte Fur Chemie, 2014, 145, 7, 1089-1099Izdavač:
- Springer Wien, Wien
Finansiranje / projekti:
- Interakcije prirodnih proizvoda, njihovih derivata i kompleksnih jedinjenja sa proteinima i nukleinskim kiselinama (RS-MESTD-Basic Research (BR or ON)-172055)
- Modulacija signalnih puteva koji kontrolišu intracelularni energetski balans u terapiji tumora i neuro-imuno-endokrinih poremećaja (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-41025)
- Razvoj novih inkapsulacionih i enzimskih tehnologija za proizvodnju biokatalizatora i biološki aktivnih komponenata hrane u cilju povećanja njene konkurentnosti, kvaliteta i bezbednosti (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-46010)
Napomena:
- Supplementary material: http://cherry.chem.bg.ac.rs/handle/123456789/3683
DOI: 10.1007/s00706-014-1197-6
ISSN: 0026-9247
WoS: 000337046200006
Scopus: 2-s2.0-84902270174
Institucija/grupa
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Filipović, Nenad R. AU - Polović, Natalija AU - Rašković, Brankica AU - Misirlić-Denčić, Sonja AU - Dulović, Marija AU - Savić, Milena AU - Nikšić, Miomir AU - Mitić, Dragana AU - Anđelković, Katarina K. AU - Todorović, Tamara PY - 2014 UR - https://cherry.chem.bg.ac.rs/handle/123456789/1787 AB - New square-planar Pd(II) and Pt(II) complexes with 8-quinolinecarboxaldehyde selenosemicarbazone have been synthesized and characterized by use of elemental analysis, molar conductivity measurements, and IR and NMR spectroscopy. The cytotoxic activity of the ligand, new Pt(II) and Pd(II) compounds, and previously synthesized Pd(II), Pt(II), Cd(II), and Ni(II) complexes with the analogous ligand, 2-quinolinecarboxaldehyde selenosemicarbazone, was tested against two human cancer cell lines: lung carcinoma (H460) and glioma (U251). The potential of these compounds to induce perturbations of the H460 cell cycle was also evaluated. These substances had an excellent radical-scavenging effect against ABTS radical cations. The best antimicrobial activity, among two yeasts and eight bacterial strains tested, was against Bacillus cereus. PB - Springer Wien, Wien T2 - Monatshefte Fur Chemie T1 - Biological activity of two isomeric N-heteroaromatic selenosemicarbazones and their metal complexes VL - 145 IS - 7 SP - 1089 EP - 1099 DO - 10.1007/s00706-014-1197-6 ER -
@article{ author = "Filipović, Nenad R. and Polović, Natalija and Rašković, Brankica and Misirlić-Denčić, Sonja and Dulović, Marija and Savić, Milena and Nikšić, Miomir and Mitić, Dragana and Anđelković, Katarina K. and Todorović, Tamara", year = "2014", abstract = "New square-planar Pd(II) and Pt(II) complexes with 8-quinolinecarboxaldehyde selenosemicarbazone have been synthesized and characterized by use of elemental analysis, molar conductivity measurements, and IR and NMR spectroscopy. The cytotoxic activity of the ligand, new Pt(II) and Pd(II) compounds, and previously synthesized Pd(II), Pt(II), Cd(II), and Ni(II) complexes with the analogous ligand, 2-quinolinecarboxaldehyde selenosemicarbazone, was tested against two human cancer cell lines: lung carcinoma (H460) and glioma (U251). The potential of these compounds to induce perturbations of the H460 cell cycle was also evaluated. These substances had an excellent radical-scavenging effect against ABTS radical cations. The best antimicrobial activity, among two yeasts and eight bacterial strains tested, was against Bacillus cereus.", publisher = "Springer Wien, Wien", journal = "Monatshefte Fur Chemie", title = "Biological activity of two isomeric N-heteroaromatic selenosemicarbazones and their metal complexes", volume = "145", number = "7", pages = "1089-1099", doi = "10.1007/s00706-014-1197-6" }
Filipović, N. R., Polović, N., Rašković, B., Misirlić-Denčić, S., Dulović, M., Savić, M., Nikšić, M., Mitić, D., Anđelković, K. K.,& Todorović, T.. (2014). Biological activity of two isomeric N-heteroaromatic selenosemicarbazones and their metal complexes. in Monatshefte Fur Chemie Springer Wien, Wien., 145(7), 1089-1099. https://doi.org/10.1007/s00706-014-1197-6
Filipović NR, Polović N, Rašković B, Misirlić-Denčić S, Dulović M, Savić M, Nikšić M, Mitić D, Anđelković KK, Todorović T. Biological activity of two isomeric N-heteroaromatic selenosemicarbazones and their metal complexes. in Monatshefte Fur Chemie. 2014;145(7):1089-1099. doi:10.1007/s00706-014-1197-6 .
Filipović, Nenad R., Polović, Natalija, Rašković, Brankica, Misirlić-Denčić, Sonja, Dulović, Marija, Savić, Milena, Nikšić, Miomir, Mitić, Dragana, Anđelković, Katarina K., Todorović, Tamara, "Biological activity of two isomeric N-heteroaromatic selenosemicarbazones and their metal complexes" in Monatshefte Fur Chemie, 145, no. 7 (2014):1089-1099, https://doi.org/10.1007/s00706-014-1197-6 . .