Novel methylene bridged ethylenediamine-type ligands: synthesis and spectral characterization
2014
Аутори
Mihajlović-Lalić, LjiljanaSavić, Aleksandar
Brađan, Gabrijela
Sabo, Tibor
Grgurić-Šipka, Sanja
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The synthesis of two new organic compounds, diisobutyl- and diisopentyl (S,S)-alpha(1),alpha(3)-bis(cyclohexylmethyl-1,3-imidazolidinediacetate is reported herein. The one-pot procedure was realized by the addition of the reducing agent and carbonyl compound into a methanolic solution of the parent compounds (isobutyl and isopentyl esters of (S,S)-alpha,alpha '-(1,2-ethanediyldiimino)bis[cyclohexanepropanoic acid] in appropriate stoichiometric ratios. The compounds were fully characterized by infrared, ESI-MS, 1D (H-1 and C-13) and 2D (COSY, HSQC and HMBC) NMR spectroscopy and elemental analysis. The spectral data confirmed the presence of the -CH2- group introduced between the nitrogen atoms of the ethylenediamine moiety, revealing a neutral form of the potential bidentate ligand.
Кључне речи:
cyclohexyl derivatives / ethylenediamine / amine ligands / potential drugsИзвор:
Journal of the Serbian Chemical Society, 2014, 79, 10, 1199-1204Издавач:
- Serbian Chemical Soc, Belgrade
Финансирање / пројекти:
- Reinforcement of the Faculty of Chemistry, University of Belgrade, towards becoming a Center of Excellence in the region of WB for Molecular Biotechnology and Food research (EU-FP7-256716)
- Рационални дизајн и синтеза биолошки активних и координационих једињења и функционалних материјала, релевантних у (био)нанотехнологији (RS-MESTD-Basic Research (BR or ON)-172035)
DOI: 10.2298/JSC140212042M
ISSN: 0352-5139
WoS: 000344444800001
Scopus: 2-s2.0-84920721049
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Mihajlović-Lalić, Ljiljana AU - Savić, Aleksandar AU - Brađan, Gabrijela AU - Sabo, Tibor AU - Grgurić-Šipka, Sanja PY - 2014 UR - https://cherry.chem.bg.ac.rs/handle/123456789/1874 AB - The synthesis of two new organic compounds, diisobutyl- and diisopentyl (S,S)-alpha(1),alpha(3)-bis(cyclohexylmethyl-1,3-imidazolidinediacetate is reported herein. The one-pot procedure was realized by the addition of the reducing agent and carbonyl compound into a methanolic solution of the parent compounds (isobutyl and isopentyl esters of (S,S)-alpha,alpha '-(1,2-ethanediyldiimino)bis[cyclohexanepropanoic acid] in appropriate stoichiometric ratios. The compounds were fully characterized by infrared, ESI-MS, 1D (H-1 and C-13) and 2D (COSY, HSQC and HMBC) NMR spectroscopy and elemental analysis. The spectral data confirmed the presence of the -CH2- group introduced between the nitrogen atoms of the ethylenediamine moiety, revealing a neutral form of the potential bidentate ligand. PB - Serbian Chemical Soc, Belgrade T2 - Journal of the Serbian Chemical Society T1 - Novel methylene bridged ethylenediamine-type ligands: synthesis and spectral characterization VL - 79 IS - 10 SP - 1199 EP - 1204 DO - 10.2298/JSC140212042M ER -
@article{ author = "Mihajlović-Lalić, Ljiljana and Savić, Aleksandar and Brađan, Gabrijela and Sabo, Tibor and Grgurić-Šipka, Sanja", year = "2014", abstract = "The synthesis of two new organic compounds, diisobutyl- and diisopentyl (S,S)-alpha(1),alpha(3)-bis(cyclohexylmethyl-1,3-imidazolidinediacetate is reported herein. The one-pot procedure was realized by the addition of the reducing agent and carbonyl compound into a methanolic solution of the parent compounds (isobutyl and isopentyl esters of (S,S)-alpha,alpha '-(1,2-ethanediyldiimino)bis[cyclohexanepropanoic acid] in appropriate stoichiometric ratios. The compounds were fully characterized by infrared, ESI-MS, 1D (H-1 and C-13) and 2D (COSY, HSQC and HMBC) NMR spectroscopy and elemental analysis. The spectral data confirmed the presence of the -CH2- group introduced between the nitrogen atoms of the ethylenediamine moiety, revealing a neutral form of the potential bidentate ligand.", publisher = "Serbian Chemical Soc, Belgrade", journal = "Journal of the Serbian Chemical Society", title = "Novel methylene bridged ethylenediamine-type ligands: synthesis and spectral characterization", volume = "79", number = "10", pages = "1199-1204", doi = "10.2298/JSC140212042M" }
Mihajlović-Lalić, L., Savić, A., Brađan, G., Sabo, T.,& Grgurić-Šipka, S.. (2014). Novel methylene bridged ethylenediamine-type ligands: synthesis and spectral characterization. in Journal of the Serbian Chemical Society Serbian Chemical Soc, Belgrade., 79(10), 1199-1204. https://doi.org/10.2298/JSC140212042M
Mihajlović-Lalić L, Savić A, Brađan G, Sabo T, Grgurić-Šipka S. Novel methylene bridged ethylenediamine-type ligands: synthesis and spectral characterization. in Journal of the Serbian Chemical Society. 2014;79(10):1199-1204. doi:10.2298/JSC140212042M .
Mihajlović-Lalić, Ljiljana, Savić, Aleksandar, Brađan, Gabrijela, Sabo, Tibor, Grgurić-Šipka, Sanja, "Novel methylene bridged ethylenediamine-type ligands: synthesis and spectral characterization" in Journal of the Serbian Chemical Society, 79, no. 10 (2014):1199-1204, https://doi.org/10.2298/JSC140212042M . .