Total synthesis of (+)-swainsonine and (+)-8-epi-swainsonine
Само за регистроване кориснике
2014
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Enantioselective synthesis of (+)-swainsonine was achieved in 9 steps, with 24% overall yield. The key feature of the synthesis is the tactical combination of reactions: organocatalyzed aldolization/reductive amination, which allows for a rapid construction of highly functionalized heterocyclic systems. In a similar way (+)-8-epi-swainsonine was synthesized (7 steps, 28%).
Извор:
RSC Advances, 2014, 4, 96, 53722-53724Издавач:
- Royal Soc Chemistry, Cambridge
Финансирање / пројекти:
- Развој нових синтетичких метода и њихова примена у синтези природних производа и биолошки активних једињења (RS-MESTD-Basic Research (BR or ON)-172027)
- Serbian Academy of Sciences and Arts [F193]
DOI: 10.1039/c4ra11978a
ISSN: 2046-2069
WoS: 000344468800042
Scopus: 2-s2.0-84908409752
Колекције
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Trajković, Milos AU - Balanac, Vesna AU - Ferjančić, Zorana AU - Saičić, Radomir PY - 2014 UR - https://cherry.chem.bg.ac.rs/handle/123456789/1876 AB - Enantioselective synthesis of (+)-swainsonine was achieved in 9 steps, with 24% overall yield. The key feature of the synthesis is the tactical combination of reactions: organocatalyzed aldolization/reductive amination, which allows for a rapid construction of highly functionalized heterocyclic systems. In a similar way (+)-8-epi-swainsonine was synthesized (7 steps, 28%). PB - Royal Soc Chemistry, Cambridge T2 - RSC Advances T1 - Total synthesis of (+)-swainsonine and (+)-8-epi-swainsonine VL - 4 IS - 96 SP - 53722 EP - 53724 DO - 10.1039/c4ra11978a ER -
@article{ author = "Trajković, Milos and Balanac, Vesna and Ferjančić, Zorana and Saičić, Radomir", year = "2014", abstract = "Enantioselective synthesis of (+)-swainsonine was achieved in 9 steps, with 24% overall yield. The key feature of the synthesis is the tactical combination of reactions: organocatalyzed aldolization/reductive amination, which allows for a rapid construction of highly functionalized heterocyclic systems. In a similar way (+)-8-epi-swainsonine was synthesized (7 steps, 28%).", publisher = "Royal Soc Chemistry, Cambridge", journal = "RSC Advances", title = "Total synthesis of (+)-swainsonine and (+)-8-epi-swainsonine", volume = "4", number = "96", pages = "53722-53724", doi = "10.1039/c4ra11978a" }
Trajković, M., Balanac, V., Ferjančić, Z.,& Saičić, R.. (2014). Total synthesis of (+)-swainsonine and (+)-8-epi-swainsonine. in RSC Advances Royal Soc Chemistry, Cambridge., 4(96), 53722-53724. https://doi.org/10.1039/c4ra11978a
Trajković M, Balanac V, Ferjančić Z, Saičić R. Total synthesis of (+)-swainsonine and (+)-8-epi-swainsonine. in RSC Advances. 2014;4(96):53722-53724. doi:10.1039/c4ra11978a .
Trajković, Milos, Balanac, Vesna, Ferjančić, Zorana, Saičić, Radomir, "Total synthesis of (+)-swainsonine and (+)-8-epi-swainsonine" in RSC Advances, 4, no. 96 (2014):53722-53724, https://doi.org/10.1039/c4ra11978a . .