Influence of organic modifiers on RP-TLC determination of lipophilicity of some polydentate Schiff bases
Samo za registrovane korisnike
2015
Autori
Perušković, Danica S.Daric, Branka
Blagus, Anita
Stevanović, Nikola R.
Pavlović, Aleksandra V.
Lolić, Aleksandar
Baošić, Rada
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
The lipophilic character of polydentate Schiff bases was investigated by reversed-phase thin-layer chromatography. In order to determine retention parameter as a measure of the lipophilicity of the tested compounds, three different binary solvent systems, composed of water and organic modifier (methanol, acetonitrile, and tetrahydrofuran), were used. Lipophilicity parameters together with 2D molecular descriptors were subjected to the multivariate statistical analysis. Principal component analysis was employed to reveal the most influential factors governing the lipophilicity of the investigated compounds. Finally, the influence of organic modifier on determination of lipophilicity parameters was discussed.
Ključne reči:
Schiff bases / RP-TLC / PCA / Lipophilicity / Molecular modeling / BioinformaticsIzvor:
Monatshefte Fur Chemie, 2015, 146, 1, 1-6Izdavač:
- Springer Wien, Wien
Finansiranje / projekti:
- Korelacija strukture i osobina prirodnih i sintetičkih molekula i njihovih kompleksa sa metalima (RS-MESTD-Basic Research (BR or ON)-172017)
DOI: 10.1007/s00706-014-1313-7
ISSN: 0026-9247
WoS: 000347161300001
Scopus: 2-s2.0-84921937430
Kolekcije
Institucija/grupa
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Perušković, Danica S. AU - Daric, Branka AU - Blagus, Anita AU - Stevanović, Nikola R. AU - Pavlović, Aleksandra V. AU - Lolić, Aleksandar AU - Baošić, Rada PY - 2015 UR - https://cherry.chem.bg.ac.rs/handle/123456789/1894 AB - The lipophilic character of polydentate Schiff bases was investigated by reversed-phase thin-layer chromatography. In order to determine retention parameter as a measure of the lipophilicity of the tested compounds, three different binary solvent systems, composed of water and organic modifier (methanol, acetonitrile, and tetrahydrofuran), were used. Lipophilicity parameters together with 2D molecular descriptors were subjected to the multivariate statistical analysis. Principal component analysis was employed to reveal the most influential factors governing the lipophilicity of the investigated compounds. Finally, the influence of organic modifier on determination of lipophilicity parameters was discussed. PB - Springer Wien, Wien T2 - Monatshefte Fur Chemie T1 - Influence of organic modifiers on RP-TLC determination of lipophilicity of some polydentate Schiff bases VL - 146 IS - 1 SP - 1 EP - 6 DO - 10.1007/s00706-014-1313-7 ER -
@article{ author = "Perušković, Danica S. and Daric, Branka and Blagus, Anita and Stevanović, Nikola R. and Pavlović, Aleksandra V. and Lolić, Aleksandar and Baošić, Rada", year = "2015", abstract = "The lipophilic character of polydentate Schiff bases was investigated by reversed-phase thin-layer chromatography. In order to determine retention parameter as a measure of the lipophilicity of the tested compounds, three different binary solvent systems, composed of water and organic modifier (methanol, acetonitrile, and tetrahydrofuran), were used. Lipophilicity parameters together with 2D molecular descriptors were subjected to the multivariate statistical analysis. Principal component analysis was employed to reveal the most influential factors governing the lipophilicity of the investigated compounds. Finally, the influence of organic modifier on determination of lipophilicity parameters was discussed.", publisher = "Springer Wien, Wien", journal = "Monatshefte Fur Chemie", title = "Influence of organic modifiers on RP-TLC determination of lipophilicity of some polydentate Schiff bases", volume = "146", number = "1", pages = "1-6", doi = "10.1007/s00706-014-1313-7" }
Perušković, D. S., Daric, B., Blagus, A., Stevanović, N. R., Pavlović, A. V., Lolić, A.,& Baošić, R.. (2015). Influence of organic modifiers on RP-TLC determination of lipophilicity of some polydentate Schiff bases. in Monatshefte Fur Chemie Springer Wien, Wien., 146(1), 1-6. https://doi.org/10.1007/s00706-014-1313-7
Perušković DS, Daric B, Blagus A, Stevanović NR, Pavlović AV, Lolić A, Baošić R. Influence of organic modifiers on RP-TLC determination of lipophilicity of some polydentate Schiff bases. in Monatshefte Fur Chemie. 2015;146(1):1-6. doi:10.1007/s00706-014-1313-7 .
Perušković, Danica S., Daric, Branka, Blagus, Anita, Stevanović, Nikola R., Pavlović, Aleksandra V., Lolić, Aleksandar, Baošić, Rada, "Influence of organic modifiers on RP-TLC determination of lipophilicity of some polydentate Schiff bases" in Monatshefte Fur Chemie, 146, no. 1 (2015):1-6, https://doi.org/10.1007/s00706-014-1313-7 . .