Cadmium(II) complexes of 5-bromo-salicylaldehyde and alpha-diimines: Synthesis, structure and interaction with calf-thymus DNA and albumins
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2016
Authors
Zianna, AriadniŠumar-Ristović, Maja
Psomas, George
Hatzidimitriou, Antonis
Coutouli-Argyropoulou, Evdoxia
Lalia-Kantouri, Maria
Article (Published version)
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Five Cd(II) complexes, four dinuclear (1-4) and a mononuclear one (5), with the anion of 5-Br-salicylaldehyde (5-Br-salo(-)), were synthesized and characterized as [Cd(5-Br-salo)(2)(CH3OH)](2) (1), [Cd(5-Br-salo)(2) (bipy)](2) (2), [Cd(5-Br-salo)(2)(phen)](2) (3), [Cd(5-Br-salo)(neoc)(NO3)](2) (4) and [Cd(5-Br-salo)(2)(dpamH)] (5). The complexes were characterized by spectroscopy (IR, UV-vis, H-1 NMR), elemental analysis and molar conductivity measurements. The structures for three complexes (2, 3 and 5) were determined by X-ray crystallography providing different coordination modes of the 5-Br-salicylaldehydo ligand. The complexes bind to DNA mainly by intercalation, as concluded by the viscosity measurements and the EB-displacement studies from the EB-DNA complex and present high DNA-binding constants (K-b), as calculated by the Wolfe-Shimer equation and plots. The interaction of the complexes with serum albumins was studied by fluorescence emission spectroscopy and the determined bi...nding constants exhibit relative high values. (C) 2016 Elsevier Ltd. All rights reserved.
Keywords:
Cadmium(II) complexes / Crystal structure / Interaction with calf-thymus DNA / Competitive studies with ethidium bromide / Interaction with serum albuminsSource:
Polyhedron, 2016, 107, 136-147Publisher:
- Pergamon-Elsevier Science Ltd, Oxford
Funding / projects:
- program of Aristeia, Aristotle University of Thessaloniki, Greece
Note:
- Supplementary material: http://cherry.chem.bg.ac.rs/handle/123456789/3394
DOI: 10.1016/j.poly.2016.01.020
ISSN: 0277-5387
WoS: 000374613700016
Scopus: 2-s2.0-84957868362
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Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Zianna, Ariadni AU - Šumar-Ristović, Maja AU - Psomas, George AU - Hatzidimitriou, Antonis AU - Coutouli-Argyropoulou, Evdoxia AU - Lalia-Kantouri, Maria PY - 2016 UR - https://cherry.chem.bg.ac.rs/handle/123456789/1923 AB - Five Cd(II) complexes, four dinuclear (1-4) and a mononuclear one (5), with the anion of 5-Br-salicylaldehyde (5-Br-salo(-)), were synthesized and characterized as [Cd(5-Br-salo)(2)(CH3OH)](2) (1), [Cd(5-Br-salo)(2) (bipy)](2) (2), [Cd(5-Br-salo)(2)(phen)](2) (3), [Cd(5-Br-salo)(neoc)(NO3)](2) (4) and [Cd(5-Br-salo)(2)(dpamH)] (5). The complexes were characterized by spectroscopy (IR, UV-vis, H-1 NMR), elemental analysis and molar conductivity measurements. The structures for three complexes (2, 3 and 5) were determined by X-ray crystallography providing different coordination modes of the 5-Br-salicylaldehydo ligand. The complexes bind to DNA mainly by intercalation, as concluded by the viscosity measurements and the EB-displacement studies from the EB-DNA complex and present high DNA-binding constants (K-b), as calculated by the Wolfe-Shimer equation and plots. The interaction of the complexes with serum albumins was studied by fluorescence emission spectroscopy and the determined binding constants exhibit relative high values. (C) 2016 Elsevier Ltd. All rights reserved. PB - Pergamon-Elsevier Science Ltd, Oxford T2 - Polyhedron T1 - Cadmium(II) complexes of 5-bromo-salicylaldehyde and alpha-diimines: Synthesis, structure and interaction with calf-thymus DNA and albumins VL - 107 SP - 136 EP - 147 DO - 10.1016/j.poly.2016.01.020 ER -
@article{ author = "Zianna, Ariadni and Šumar-Ristović, Maja and Psomas, George and Hatzidimitriou, Antonis and Coutouli-Argyropoulou, Evdoxia and Lalia-Kantouri, Maria", year = "2016", abstract = "Five Cd(II) complexes, four dinuclear (1-4) and a mononuclear one (5), with the anion of 5-Br-salicylaldehyde (5-Br-salo(-)), were synthesized and characterized as [Cd(5-Br-salo)(2)(CH3OH)](2) (1), [Cd(5-Br-salo)(2) (bipy)](2) (2), [Cd(5-Br-salo)(2)(phen)](2) (3), [Cd(5-Br-salo)(neoc)(NO3)](2) (4) and [Cd(5-Br-salo)(2)(dpamH)] (5). The complexes were characterized by spectroscopy (IR, UV-vis, H-1 NMR), elemental analysis and molar conductivity measurements. The structures for three complexes (2, 3 and 5) were determined by X-ray crystallography providing different coordination modes of the 5-Br-salicylaldehydo ligand. The complexes bind to DNA mainly by intercalation, as concluded by the viscosity measurements and the EB-displacement studies from the EB-DNA complex and present high DNA-binding constants (K-b), as calculated by the Wolfe-Shimer equation and plots. The interaction of the complexes with serum albumins was studied by fluorescence emission spectroscopy and the determined binding constants exhibit relative high values. (C) 2016 Elsevier Ltd. All rights reserved.", publisher = "Pergamon-Elsevier Science Ltd, Oxford", journal = "Polyhedron", title = "Cadmium(II) complexes of 5-bromo-salicylaldehyde and alpha-diimines: Synthesis, structure and interaction with calf-thymus DNA and albumins", volume = "107", pages = "136-147", doi = "10.1016/j.poly.2016.01.020" }
Zianna, A., Šumar-Ristović, M., Psomas, G., Hatzidimitriou, A., Coutouli-Argyropoulou, E.,& Lalia-Kantouri, M.. (2016). Cadmium(II) complexes of 5-bromo-salicylaldehyde and alpha-diimines: Synthesis, structure and interaction with calf-thymus DNA and albumins. in Polyhedron Pergamon-Elsevier Science Ltd, Oxford., 107, 136-147. https://doi.org/10.1016/j.poly.2016.01.020
Zianna A, Šumar-Ristović M, Psomas G, Hatzidimitriou A, Coutouli-Argyropoulou E, Lalia-Kantouri M. Cadmium(II) complexes of 5-bromo-salicylaldehyde and alpha-diimines: Synthesis, structure and interaction with calf-thymus DNA and albumins. in Polyhedron. 2016;107:136-147. doi:10.1016/j.poly.2016.01.020 .
Zianna, Ariadni, Šumar-Ristović, Maja, Psomas, George, Hatzidimitriou, Antonis, Coutouli-Argyropoulou, Evdoxia, Lalia-Kantouri, Maria, "Cadmium(II) complexes of 5-bromo-salicylaldehyde and alpha-diimines: Synthesis, structure and interaction with calf-thymus DNA and albumins" in Polyhedron, 107 (2016):136-147, https://doi.org/10.1016/j.poly.2016.01.020 . .