Biomarkers of oxidative stress and metal accumulation in marsh frog (Pelophylax ridibundus)
Само за регистроване кориснике
2016
Аутори
Borković-Mitić, Slavica S.Prokić, Marko D.
Krizmanić, Imre I.
Mutić, Jelena
Trifković, Jelena
Gavrić, Jelena P.
Despotović, Svetlana G.
Gavrilović, Branka R.
Radovanović, Tijana B.
Pavlović, Slađan Z.
Saičić, Zorica S.
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
To understand the effect of metals on the marsh frog Pelophylax ridibundus and the possible environment-induced changes in oxidative stress enzymes, we determined the concentrations of 18 metals: Al, As, Ba, Ca, Cd, Co, Cr, Cu, Fe, Ga, Hg, In, Li, Mn, Ni, Pb, Sr, and Zn, in the tissues (liver, skin, and muscle) and water samples collected from different locations in Serbia. The activities of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione reductase (GR), glutathione S-transferase (GST), acetylcholinesterase (AChE), and changes in concentrations of reduced glutathione (GSH) and sulfhydryl groups (SH) were analyzed in the tissues of the sampled frogs. The concentrations of Al, Cd, Co, Cr, Cu, Fe, Ga, Hg, and Ni were highest in the liver, whereas those of Ba, Ca, Li, Mn, Pb, Sr, and Zn were highest in the skin. Hg correlated positively with liver SOD (in frogs from Danube-Tisza-Danube Canal (DTD)), muscle CAT (DTD), and muscle GST Ponjavica River (...PO); Pb demonstrated a strong positive correlation with liver GR in frogs from Mt. Fruka Gora (FG); Cd only exhibited a positive correlation with AChE in the skin of frogs from DTD. In the skin, Zn correlated positively with AChE (DTD), SH groups (PO), and CAT (FG), and negatively with CAT, GST, and SH in the liver of frogs from DTD. Examination of these oxidative stress biomarkers, together with analysis of metal accumulation in the liver and skin of marsh frogs, provides a powerful tool for the assessment of metal pollution.
Кључне речи:
Antioxidative system / Biomonitoring / Marsh frogs / Liver / Skin / Muscle / MetalsИзвор:
Environmental Science and Pollution Research, 2016, 23, 10, 9649-9659Издавач:
- Springer Heidelberg, Heidelberg
Финансирање / пројекти:
- Молекуларно физиолошки биомониторинг аеробних организама заснован на одређивању биохемијских биомаркера оксидационог стреса (RS-MESTD-Basic Research (BR or ON)-173041)
Напомена:
- Supplementary material: http://cherry.chem.bg.ac.rs/handle/123456789/3392
DOI: 10.1007/s11356-016-6194-3
ISSN: 0944-1344
PubMed: 26846240
WoS: 000376421400038
Scopus: 2-s2.0-84957569534
Колекције
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Borković-Mitić, Slavica S. AU - Prokić, Marko D. AU - Krizmanić, Imre I. AU - Mutić, Jelena AU - Trifković, Jelena AU - Gavrić, Jelena P. AU - Despotović, Svetlana G. AU - Gavrilović, Branka R. AU - Radovanović, Tijana B. AU - Pavlović, Slađan Z. AU - Saičić, Zorica S. PY - 2016 UR - https://cherry.chem.bg.ac.rs/handle/123456789/1941 AB - To understand the effect of metals on the marsh frog Pelophylax ridibundus and the possible environment-induced changes in oxidative stress enzymes, we determined the concentrations of 18 metals: Al, As, Ba, Ca, Cd, Co, Cr, Cu, Fe, Ga, Hg, In, Li, Mn, Ni, Pb, Sr, and Zn, in the tissues (liver, skin, and muscle) and water samples collected from different locations in Serbia. The activities of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione reductase (GR), glutathione S-transferase (GST), acetylcholinesterase (AChE), and changes in concentrations of reduced glutathione (GSH) and sulfhydryl groups (SH) were analyzed in the tissues of the sampled frogs. The concentrations of Al, Cd, Co, Cr, Cu, Fe, Ga, Hg, and Ni were highest in the liver, whereas those of Ba, Ca, Li, Mn, Pb, Sr, and Zn were highest in the skin. Hg correlated positively with liver SOD (in frogs from Danube-Tisza-Danube Canal (DTD)), muscle CAT (DTD), and muscle GST Ponjavica River (PO); Pb demonstrated a strong positive correlation with liver GR in frogs from Mt. Fruka Gora (FG); Cd only exhibited a positive correlation with AChE in the skin of frogs from DTD. In the skin, Zn correlated positively with AChE (DTD), SH groups (PO), and CAT (FG), and negatively with CAT, GST, and SH in the liver of frogs from DTD. Examination of these oxidative stress biomarkers, together with analysis of metal accumulation in the liver and skin of marsh frogs, provides a powerful tool for the assessment of metal pollution. PB - Springer Heidelberg, Heidelberg T2 - Environmental Science and Pollution Research T1 - Biomarkers of oxidative stress and metal accumulation in marsh frog (Pelophylax ridibundus) VL - 23 IS - 10 SP - 9649 EP - 9659 DO - 10.1007/s11356-016-6194-3 ER -
@article{ author = "Borković-Mitić, Slavica S. and Prokić, Marko D. and Krizmanić, Imre I. and Mutić, Jelena and Trifković, Jelena and Gavrić, Jelena P. and Despotović, Svetlana G. and Gavrilović, Branka R. and Radovanović, Tijana B. and Pavlović, Slađan Z. and Saičić, Zorica S.", year = "2016", abstract = "To understand the effect of metals on the marsh frog Pelophylax ridibundus and the possible environment-induced changes in oxidative stress enzymes, we determined the concentrations of 18 metals: Al, As, Ba, Ca, Cd, Co, Cr, Cu, Fe, Ga, Hg, In, Li, Mn, Ni, Pb, Sr, and Zn, in the tissues (liver, skin, and muscle) and water samples collected from different locations in Serbia. The activities of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione reductase (GR), glutathione S-transferase (GST), acetylcholinesterase (AChE), and changes in concentrations of reduced glutathione (GSH) and sulfhydryl groups (SH) were analyzed in the tissues of the sampled frogs. The concentrations of Al, Cd, Co, Cr, Cu, Fe, Ga, Hg, and Ni were highest in the liver, whereas those of Ba, Ca, Li, Mn, Pb, Sr, and Zn were highest in the skin. Hg correlated positively with liver SOD (in frogs from Danube-Tisza-Danube Canal (DTD)), muscle CAT (DTD), and muscle GST Ponjavica River (PO); Pb demonstrated a strong positive correlation with liver GR in frogs from Mt. Fruka Gora (FG); Cd only exhibited a positive correlation with AChE in the skin of frogs from DTD. In the skin, Zn correlated positively with AChE (DTD), SH groups (PO), and CAT (FG), and negatively with CAT, GST, and SH in the liver of frogs from DTD. Examination of these oxidative stress biomarkers, together with analysis of metal accumulation in the liver and skin of marsh frogs, provides a powerful tool for the assessment of metal pollution.", publisher = "Springer Heidelberg, Heidelberg", journal = "Environmental Science and Pollution Research", title = "Biomarkers of oxidative stress and metal accumulation in marsh frog (Pelophylax ridibundus)", volume = "23", number = "10", pages = "9649-9659", doi = "10.1007/s11356-016-6194-3" }
Borković-Mitić, S. S., Prokić, M. D., Krizmanić, I. I., Mutić, J., Trifković, J., Gavrić, J. P., Despotović, S. G., Gavrilović, B. R., Radovanović, T. B., Pavlović, S. Z.,& Saičić, Z. S.. (2016). Biomarkers of oxidative stress and metal accumulation in marsh frog (Pelophylax ridibundus). in Environmental Science and Pollution Research Springer Heidelberg, Heidelberg., 23(10), 9649-9659. https://doi.org/10.1007/s11356-016-6194-3
Borković-Mitić SS, Prokić MD, Krizmanić II, Mutić J, Trifković J, Gavrić JP, Despotović SG, Gavrilović BR, Radovanović TB, Pavlović SZ, Saičić ZS. Biomarkers of oxidative stress and metal accumulation in marsh frog (Pelophylax ridibundus). in Environmental Science and Pollution Research. 2016;23(10):9649-9659. doi:10.1007/s11356-016-6194-3 .
Borković-Mitić, Slavica S., Prokić, Marko D., Krizmanić, Imre I., Mutić, Jelena, Trifković, Jelena, Gavrić, Jelena P., Despotović, Svetlana G., Gavrilović, Branka R., Radovanović, Tijana B., Pavlović, Slađan Z., Saičić, Zorica S., "Biomarkers of oxidative stress and metal accumulation in marsh frog (Pelophylax ridibundus)" in Environmental Science and Pollution Research, 23, no. 10 (2016):9649-9659, https://doi.org/10.1007/s11356-016-6194-3 . .