Interaction of dinuclear cadmium(II) 5-Cl-salicylaldehyde complexes with calf-thymus DNA
Само за регистроване кориснике
2016
Аутори
Šumar-Ristović, MajaZianna, Ariadni
Psomas, George
Hatzidimitriou, Antonios G.
Coutouli-Argyropoulou, Evdoxia
Lalia-Kantouri, Maria
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Five dinuclear Cd(II) complexes with the anion of 5-Cl-salicylaldehyde (5-Cl-saloH) were synthesized in the absence or presence of the alpha-diimines: 2,2'-bipyridine (bipy), 1,10-phenanthroline (phen), 2,9-dimethyl-1,10-henanthroline (neoc) or 2,2'-dipyridylamine (dpamH) and characterized as [Cd(5-Cl-salo)(2)(CH3OH)](2) (1), [Cd(5-Cl-salo)(2)(bipy)](2) (2), [Cd(5-Cl-salo)(2)(phen)](2) (3), [Cd(5-Cl-salo)(neoc)(ONO2)](2) (4) and [Cd(5-Cl-salo)(dpamH)(ONO2)](2) (5). The complexes were characterized by spectroscopic techniques (IR, UV-vis, H-1-NMR and C-13-NMR), elemental analysis and molar conductivity measurements. The structures of four complexes (1-3 and 5) were determined by X-ray crystallography, providing all three possible coordination modes of the ligand 5-Cl-salicylaldehyde, i.e. bidentate or tridentate chelating and/or bridging mode. The complexes bind to calf-thymus (Cr) DNA mainly by intercalation, as concluded by the viscosity measurements and present relatively high DNA-bi...nding constants. The complexes exhibit significant ability to displace ethidium bromide (EB) from the EB-DNA complex, thus indirectly proving the intercalation as the most possible binding mode to Cr DNA. (C) 2016 Elsevier B.V. All rights reserved.
Кључне речи:
Cadmium(II) complexes / Crystal structure / Interaction with calf-thymus DNA / 5-Cl-salicylaldehydeИзвор:
Materials Science and Engineering. C: Materials for Biological Applications, 2016, 61, 579-590Издавач:
- Elsevier Science Bv, Amsterdam
Финансирање / пројекти:
- Aristeia, Aristotle University of Thessaloniki
Напомена:
- Supplementary material: http://cherry.chem.bg.ac.rs/handle/123456789/3544
DOI: 10.1016/j.msec.2015.12.054
ISSN: 0928-4931
PubMed: 26838886
WoS: 000370303600070
Scopus: 2-s2.0-84953790012
Колекције
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Šumar-Ristović, Maja AU - Zianna, Ariadni AU - Psomas, George AU - Hatzidimitriou, Antonios G. AU - Coutouli-Argyropoulou, Evdoxia AU - Lalia-Kantouri, Maria PY - 2016 UR - https://cherry.chem.bg.ac.rs/handle/123456789/2052 AB - Five dinuclear Cd(II) complexes with the anion of 5-Cl-salicylaldehyde (5-Cl-saloH) were synthesized in the absence or presence of the alpha-diimines: 2,2'-bipyridine (bipy), 1,10-phenanthroline (phen), 2,9-dimethyl-1,10-henanthroline (neoc) or 2,2'-dipyridylamine (dpamH) and characterized as [Cd(5-Cl-salo)(2)(CH3OH)](2) (1), [Cd(5-Cl-salo)(2)(bipy)](2) (2), [Cd(5-Cl-salo)(2)(phen)](2) (3), [Cd(5-Cl-salo)(neoc)(ONO2)](2) (4) and [Cd(5-Cl-salo)(dpamH)(ONO2)](2) (5). The complexes were characterized by spectroscopic techniques (IR, UV-vis, H-1-NMR and C-13-NMR), elemental analysis and molar conductivity measurements. The structures of four complexes (1-3 and 5) were determined by X-ray crystallography, providing all three possible coordination modes of the ligand 5-Cl-salicylaldehyde, i.e. bidentate or tridentate chelating and/or bridging mode. The complexes bind to calf-thymus (Cr) DNA mainly by intercalation, as concluded by the viscosity measurements and present relatively high DNA-binding constants. The complexes exhibit significant ability to displace ethidium bromide (EB) from the EB-DNA complex, thus indirectly proving the intercalation as the most possible binding mode to Cr DNA. (C) 2016 Elsevier B.V. All rights reserved. PB - Elsevier Science Bv, Amsterdam T2 - Materials Science and Engineering. C: Materials for Biological Applications T1 - Interaction of dinuclear cadmium(II) 5-Cl-salicylaldehyde complexes with calf-thymus DNA VL - 61 SP - 579 EP - 590 DO - 10.1016/j.msec.2015.12.054 ER -
@article{ author = "Šumar-Ristović, Maja and Zianna, Ariadni and Psomas, George and Hatzidimitriou, Antonios G. and Coutouli-Argyropoulou, Evdoxia and Lalia-Kantouri, Maria", year = "2016", abstract = "Five dinuclear Cd(II) complexes with the anion of 5-Cl-salicylaldehyde (5-Cl-saloH) were synthesized in the absence or presence of the alpha-diimines: 2,2'-bipyridine (bipy), 1,10-phenanthroline (phen), 2,9-dimethyl-1,10-henanthroline (neoc) or 2,2'-dipyridylamine (dpamH) and characterized as [Cd(5-Cl-salo)(2)(CH3OH)](2) (1), [Cd(5-Cl-salo)(2)(bipy)](2) (2), [Cd(5-Cl-salo)(2)(phen)](2) (3), [Cd(5-Cl-salo)(neoc)(ONO2)](2) (4) and [Cd(5-Cl-salo)(dpamH)(ONO2)](2) (5). The complexes were characterized by spectroscopic techniques (IR, UV-vis, H-1-NMR and C-13-NMR), elemental analysis and molar conductivity measurements. The structures of four complexes (1-3 and 5) were determined by X-ray crystallography, providing all three possible coordination modes of the ligand 5-Cl-salicylaldehyde, i.e. bidentate or tridentate chelating and/or bridging mode. The complexes bind to calf-thymus (Cr) DNA mainly by intercalation, as concluded by the viscosity measurements and present relatively high DNA-binding constants. The complexes exhibit significant ability to displace ethidium bromide (EB) from the EB-DNA complex, thus indirectly proving the intercalation as the most possible binding mode to Cr DNA. (C) 2016 Elsevier B.V. All rights reserved.", publisher = "Elsevier Science Bv, Amsterdam", journal = "Materials Science and Engineering. C: Materials for Biological Applications", title = "Interaction of dinuclear cadmium(II) 5-Cl-salicylaldehyde complexes with calf-thymus DNA", volume = "61", pages = "579-590", doi = "10.1016/j.msec.2015.12.054" }
Šumar-Ristović, M., Zianna, A., Psomas, G., Hatzidimitriou, A. G., Coutouli-Argyropoulou, E.,& Lalia-Kantouri, M.. (2016). Interaction of dinuclear cadmium(II) 5-Cl-salicylaldehyde complexes with calf-thymus DNA. in Materials Science and Engineering. C: Materials for Biological Applications Elsevier Science Bv, Amsterdam., 61, 579-590. https://doi.org/10.1016/j.msec.2015.12.054
Šumar-Ristović M, Zianna A, Psomas G, Hatzidimitriou AG, Coutouli-Argyropoulou E, Lalia-Kantouri M. Interaction of dinuclear cadmium(II) 5-Cl-salicylaldehyde complexes with calf-thymus DNA. in Materials Science and Engineering. C: Materials for Biological Applications. 2016;61:579-590. doi:10.1016/j.msec.2015.12.054 .
Šumar-Ristović, Maja, Zianna, Ariadni, Psomas, George, Hatzidimitriou, Antonios G., Coutouli-Argyropoulou, Evdoxia, Lalia-Kantouri, Maria, "Interaction of dinuclear cadmium(II) 5-Cl-salicylaldehyde complexes with calf-thymus DNA" in Materials Science and Engineering. C: Materials for Biological Applications, 61 (2016):579-590, https://doi.org/10.1016/j.msec.2015.12.054 . .