Wild Thymus capitatus Hoff. Et Link. Chemical Composition, Antioxidant and Antimicrobial Activities of the Essential Oil
Samo za registrovane korisnike
2018
Autori
Marin, MarijaNovaković, Miroslav M.
Vučković, Ivan M.
Tešević, Vele
Kolarević, Stoimir
Vuković-Gačić, Branka
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
The composition of the essential oil (EO) obtained by hydrodistillation from the leaves of Thymus capitatus Hoff. et Link. growing wild in Sythonia (Greece) was analysed by GC-FID, GC-MS and quantitative H-1 NMR spectroscopy. Thirty nine compounds were identified, representing approximately 99.0 % of the oil. Major component determined by GC-FID was carvacrol (81.8 %), followed by linalool (3.5 %) and (E)-caryophyllenc (3.5 %). Abundance of carvacrol determined by quantitative H-1 NMR spectroscopy was 74.9 % and was in reasonable agreement with GC-FID result. The oil was tested for the antioxidant activity in DPPH assay and showed a dose dependent free radical scavenging activity with EC50 value of 1.03 mu g/ml. Antimicrobial effect of the EO was tested against Gram negative, Gram positive bacteria, and fungi. The tested EO showed significant activity against fungi, especially S. cerevisiae. The most sensitive bacteria were E. coil ATCC 25922, E. fecalis and S. epidermidis. Human patho...gen Burkholderia cepacia, ATCC 25416 was used in the investigation of T capitatus for the fast time.
Ključne reči:
Thymus capitatus / essential oil / GC-FID / GC-MS / antioxidant / antimicrobialIzvor:
Journal of Essential Oil Bearing Plants, 2018, 21, 2, 388-399Izdavač:
- Taylor & Francis Ltd, Abingdon
Finansiranje / projekti:
- Bioaktivni prirodni proizvodi samoniklih, gajenih i jestivih biljaka: određivanje struktura i aktivnosti (RS-172053)
- Biološki aktivni prirodni proizvodi kao potencijalni izvori novih lekova i dijetetskih suplemenata (RS-172058)
DOI: 10.1080/0972060X.2018.1449668
ISSN: 0972-060X
WoS: 000432900400008
Scopus: 2-s2.0-85046820016
Kolekcije
Institucija/grupa
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Marin, Marija AU - Novaković, Miroslav M. AU - Vučković, Ivan M. AU - Tešević, Vele AU - Kolarević, Stoimir AU - Vuković-Gačić, Branka PY - 2018 UR - https://cherry.chem.bg.ac.rs/handle/123456789/2143 AB - The composition of the essential oil (EO) obtained by hydrodistillation from the leaves of Thymus capitatus Hoff. et Link. growing wild in Sythonia (Greece) was analysed by GC-FID, GC-MS and quantitative H-1 NMR spectroscopy. Thirty nine compounds were identified, representing approximately 99.0 % of the oil. Major component determined by GC-FID was carvacrol (81.8 %), followed by linalool (3.5 %) and (E)-caryophyllenc (3.5 %). Abundance of carvacrol determined by quantitative H-1 NMR spectroscopy was 74.9 % and was in reasonable agreement with GC-FID result. The oil was tested for the antioxidant activity in DPPH assay and showed a dose dependent free radical scavenging activity with EC50 value of 1.03 mu g/ml. Antimicrobial effect of the EO was tested against Gram negative, Gram positive bacteria, and fungi. The tested EO showed significant activity against fungi, especially S. cerevisiae. The most sensitive bacteria were E. coil ATCC 25922, E. fecalis and S. epidermidis. Human pathogen Burkholderia cepacia, ATCC 25416 was used in the investigation of T capitatus for the fast time. PB - Taylor & Francis Ltd, Abingdon T2 - Journal of Essential Oil Bearing Plants T1 - Wild Thymus capitatus Hoff. Et Link. Chemical Composition, Antioxidant and Antimicrobial Activities of the Essential Oil VL - 21 IS - 2 SP - 388 EP - 399 DO - 10.1080/0972060X.2018.1449668 ER -
@article{ author = "Marin, Marija and Novaković, Miroslav M. and Vučković, Ivan M. and Tešević, Vele and Kolarević, Stoimir and Vuković-Gačić, Branka", year = "2018", abstract = "The composition of the essential oil (EO) obtained by hydrodistillation from the leaves of Thymus capitatus Hoff. et Link. growing wild in Sythonia (Greece) was analysed by GC-FID, GC-MS and quantitative H-1 NMR spectroscopy. Thirty nine compounds were identified, representing approximately 99.0 % of the oil. Major component determined by GC-FID was carvacrol (81.8 %), followed by linalool (3.5 %) and (E)-caryophyllenc (3.5 %). Abundance of carvacrol determined by quantitative H-1 NMR spectroscopy was 74.9 % and was in reasonable agreement with GC-FID result. The oil was tested for the antioxidant activity in DPPH assay and showed a dose dependent free radical scavenging activity with EC50 value of 1.03 mu g/ml. Antimicrobial effect of the EO was tested against Gram negative, Gram positive bacteria, and fungi. The tested EO showed significant activity against fungi, especially S. cerevisiae. The most sensitive bacteria were E. coil ATCC 25922, E. fecalis and S. epidermidis. Human pathogen Burkholderia cepacia, ATCC 25416 was used in the investigation of T capitatus for the fast time.", publisher = "Taylor & Francis Ltd, Abingdon", journal = "Journal of Essential Oil Bearing Plants", title = "Wild Thymus capitatus Hoff. Et Link. Chemical Composition, Antioxidant and Antimicrobial Activities of the Essential Oil", volume = "21", number = "2", pages = "388-399", doi = "10.1080/0972060X.2018.1449668" }
Marin, M., Novaković, M. M., Vučković, I. M., Tešević, V., Kolarević, S.,& Vuković-Gačić, B.. (2018). Wild Thymus capitatus Hoff. Et Link. Chemical Composition, Antioxidant and Antimicrobial Activities of the Essential Oil. in Journal of Essential Oil Bearing Plants Taylor & Francis Ltd, Abingdon., 21(2), 388-399. https://doi.org/10.1080/0972060X.2018.1449668
Marin M, Novaković MM, Vučković IM, Tešević V, Kolarević S, Vuković-Gačić B. Wild Thymus capitatus Hoff. Et Link. Chemical Composition, Antioxidant and Antimicrobial Activities of the Essential Oil. in Journal of Essential Oil Bearing Plants. 2018;21(2):388-399. doi:10.1080/0972060X.2018.1449668 .
Marin, Marija, Novaković, Miroslav M., Vučković, Ivan M., Tešević, Vele, Kolarević, Stoimir, Vuković-Gačić, Branka, "Wild Thymus capitatus Hoff. Et Link. Chemical Composition, Antioxidant and Antimicrobial Activities of the Essential Oil" in Journal of Essential Oil Bearing Plants, 21, no. 2 (2018):388-399, https://doi.org/10.1080/0972060X.2018.1449668 . .