Evaluation of Food Allergy in Children by Skin Prick Tests with Commercial Extracts and Fresh Foods, Specific IgE and, Open Oral Food Challenge: Our Five Years Experience in Food Allergy Work-up
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Аутори
Zivanovic, MirjanaAtanasković-Marković, Marina
Međo, Biljana
Gavrović-Jankulović, Marija
Smiljanić, Katarina
Tmušić, Vladimir
Đurić, Vojislav
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
IgE-mediated food allergy affects 6-8% of children. Our study aimed to define the correlations between the results obtained with skin prick tests (SPTs) using commercial extracts and fresh foods, and the correlations between these result and those obtained with specific IgE (sIgE) and/or challenge. Children aged from 2 months to 6 years were recruited prospectively. Overall 571 children were positive to one food. In all children we performed SPT using commercial extracts of suspected food and fresh foods and sIgE. If SPT and sIgE test results did not correspond to the history, we performed open oral food challenge. Sensitivity of SPT with commercial extracts for all tested food was poor (3-35%), while sensitivity of fresh food skin prick tests (FFSPT) was excellent (50-100%), and showed correlation with open oral food challenge (p lt 0.001). Our results suggest that fresh food extracts are more effective in detecting sensitization and with levels of sIgE greater than class 3 could pred...ict clinical reactivity, without the need for potentially hazardous food challenges.
Кључне речи:
Children / Food hypersensitivity / Open oral food challenge / Skin test / Skin prick testingИзвор:
Iranian Journal of Allergy Asthma and Immunology, 2017, 16, 2, 127-132Издавач:
- Iranian Scientific Society Medical Entomology, Tehran
Финансирање / пројекти:
- Молекуларне особине и модификације неких респираторних и нутритивних алергена (RS-MESTD-Basic Research (BR or ON)-172024)
- Алергени, антитела, ензими и мали физиолошки значајни молекули: дизајн, структура, функција и значај (RS-MESTD-Basic Research (BR or ON)-172049)
Колекције
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Zivanovic, Mirjana AU - Atanasković-Marković, Marina AU - Međo, Biljana AU - Gavrović-Jankulović, Marija AU - Smiljanić, Katarina AU - Tmušić, Vladimir AU - Đurić, Vojislav PY - 2017 UR - https://cherry.chem.bg.ac.rs/handle/123456789/2469 AB - IgE-mediated food allergy affects 6-8% of children. Our study aimed to define the correlations between the results obtained with skin prick tests (SPTs) using commercial extracts and fresh foods, and the correlations between these result and those obtained with specific IgE (sIgE) and/or challenge. Children aged from 2 months to 6 years were recruited prospectively. Overall 571 children were positive to one food. In all children we performed SPT using commercial extracts of suspected food and fresh foods and sIgE. If SPT and sIgE test results did not correspond to the history, we performed open oral food challenge. Sensitivity of SPT with commercial extracts for all tested food was poor (3-35%), while sensitivity of fresh food skin prick tests (FFSPT) was excellent (50-100%), and showed correlation with open oral food challenge (p lt 0.001). Our results suggest that fresh food extracts are more effective in detecting sensitization and with levels of sIgE greater than class 3 could predict clinical reactivity, without the need for potentially hazardous food challenges. PB - Iranian Scientific Society Medical Entomology, Tehran T2 - Iranian Journal of Allergy Asthma and Immunology T1 - Evaluation of Food Allergy in Children by Skin Prick Tests with Commercial Extracts and Fresh Foods, Specific IgE and, Open Oral Food Challenge: Our Five Years Experience in Food Allergy Work-up VL - 16 IS - 2 SP - 127 EP - 132 UR - https://hdl.handle.net/21.15107/rcub_cherry_2469 ER -
@article{ author = "Zivanovic, Mirjana and Atanasković-Marković, Marina and Međo, Biljana and Gavrović-Jankulović, Marija and Smiljanić, Katarina and Tmušić, Vladimir and Đurić, Vojislav", year = "2017", abstract = "IgE-mediated food allergy affects 6-8% of children. Our study aimed to define the correlations between the results obtained with skin prick tests (SPTs) using commercial extracts and fresh foods, and the correlations between these result and those obtained with specific IgE (sIgE) and/or challenge. Children aged from 2 months to 6 years were recruited prospectively. Overall 571 children were positive to one food. In all children we performed SPT using commercial extracts of suspected food and fresh foods and sIgE. If SPT and sIgE test results did not correspond to the history, we performed open oral food challenge. Sensitivity of SPT with commercial extracts for all tested food was poor (3-35%), while sensitivity of fresh food skin prick tests (FFSPT) was excellent (50-100%), and showed correlation with open oral food challenge (p lt 0.001). Our results suggest that fresh food extracts are more effective in detecting sensitization and with levels of sIgE greater than class 3 could predict clinical reactivity, without the need for potentially hazardous food challenges.", publisher = "Iranian Scientific Society Medical Entomology, Tehran", journal = "Iranian Journal of Allergy Asthma and Immunology", title = "Evaluation of Food Allergy in Children by Skin Prick Tests with Commercial Extracts and Fresh Foods, Specific IgE and, Open Oral Food Challenge: Our Five Years Experience in Food Allergy Work-up", volume = "16", number = "2", pages = "127-132", url = "https://hdl.handle.net/21.15107/rcub_cherry_2469" }
Zivanovic, M., Atanasković-Marković, M., Međo, B., Gavrović-Jankulović, M., Smiljanić, K., Tmušić, V.,& Đurić, V.. (2017). Evaluation of Food Allergy in Children by Skin Prick Tests with Commercial Extracts and Fresh Foods, Specific IgE and, Open Oral Food Challenge: Our Five Years Experience in Food Allergy Work-up. in Iranian Journal of Allergy Asthma and Immunology Iranian Scientific Society Medical Entomology, Tehran., 16(2), 127-132. https://hdl.handle.net/21.15107/rcub_cherry_2469
Zivanovic M, Atanasković-Marković M, Međo B, Gavrović-Jankulović M, Smiljanić K, Tmušić V, Đurić V. Evaluation of Food Allergy in Children by Skin Prick Tests with Commercial Extracts and Fresh Foods, Specific IgE and, Open Oral Food Challenge: Our Five Years Experience in Food Allergy Work-up. in Iranian Journal of Allergy Asthma and Immunology. 2017;16(2):127-132. https://hdl.handle.net/21.15107/rcub_cherry_2469 .
Zivanovic, Mirjana, Atanasković-Marković, Marina, Međo, Biljana, Gavrović-Jankulović, Marija, Smiljanić, Katarina, Tmušić, Vladimir, Đurić, Vojislav, "Evaluation of Food Allergy in Children by Skin Prick Tests with Commercial Extracts and Fresh Foods, Specific IgE and, Open Oral Food Challenge: Our Five Years Experience in Food Allergy Work-up" in Iranian Journal of Allergy Asthma and Immunology, 16, no. 2 (2017):127-132, https://hdl.handle.net/21.15107/rcub_cherry_2469 .