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Lysine acetylation of major Chlamydia trachomatis antigens
dc.creator | Mihailović-Vesić, Jelena | |
dc.creator | Inić-Kanada, Aleksandra | |
dc.creator | Smiljanić, Katarina | |
dc.creator | Stein, Elisabeth | |
dc.creator | Barisani-Asenbauer, T. | |
dc.creator | Ćirković-Veličković, Tanja | |
dc.date.accessioned | 2018-11-22T00:34:14Z | |
dc.date.available | 2018-11-22T00:34:14Z | |
dc.date.issued | 2016 | |
dc.identifier.issn | 2212-9685 | |
dc.identifier.uri | https://cherry.chem.bg.ac.rs/handle/123456789/295 | |
dc.description.abstract | Chlamydia trachomatis (Ct) is a human pathogen causing trachoma and infertility. We investigated acetylation at lysine residues of chlamydial antigenic proteins: major outer membrane protein (MOMP), 60 kDa chaperonin (chlamydial Hsp60), elongation factor G (EF-G), enolase and the polymorphic membrane proteins PmpB, PmpE and PmpF. 60 kDa chaperonin, EF-G and PmpB showed the highest degree of acetylation. Our data show that important Ct antigens could be post-translationally modified by acetylation of lysine residues at multiple sites. Further studies are needed to investigate total acetylome of Ct and the impact PTMs might have on Ct biology and pathogenicity. © 2016. | en |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172024/RS// | |
dc.relation | info:eu-repo/grantAgreement/EC/FP7/256716/EU// | |
dc.relation | Austrian Research Promotion Agency (FFG Project Number: 822768). | |
dc.rights | openAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.source | EuPA Open Proteomics | |
dc.subject | Antigens | en |
dc.subject | Chlamydia trachomatis | en |
dc.subject | Lysine acetylation | en |
dc.subject | Mass spectrometry | en |
dc.title | Lysine acetylation of major Chlamydia trachomatis antigens | en |
dc.type | article | |
dc.rights.license | BY | |
dcterms.abstract | Стеин, Е.; Барисани-Aсенбауер, Т.; Михаиловић Весић, Јелена; Ћирковић-Величковић, Тања; Смиљанић, Катарина; Иниц-Канада, A.; | |
dc.citation.volume | 10 | |
dc.citation.spage | 63 | |
dc.citation.epage | 69 | |
dc.identifier.doi | 10.1016/j.euprot.2016.01.007 | |
dc.citation.other | 10: 63-69 | |
dc.description.other | Supplementary material: [http://cherry.chem.bg.ac.rs/handle/123456789/3563] | |
dc.type.version | publishedVersion | |
dc.identifier.scopus | 2-s2.0-84956640653 | |
dc.identifier.fulltext | https://cherry.chem.bg.ac.rs/bitstream/id/9677/293.pdf |