Determination of pyridoxine (vitamin B-6) in pharmaceuticals and urine samples using unmodified boron-doped diamond electrode
Аутори
Kuzmanović, DarkoKhan, Muslim
Mehmeti, Eda
Nazir, Ruclia
Amaizah, Naser Ramdan R.
Stanković, Dalibor
Чланак у часопису (Рецензирана верзија)
Метаподаци
Приказ свих података о документуАпстракт
Pyridoxine (vitamin B-6, VB6) was detected in pharmaceutical preparation and human urine samples by employing differential pulse voltammetry (DPV) at unmodified boron doped electrode. In Britton-Robinson buffer solution (BRBS) at pH 6, VB6 provides well defined oxidation peak at around +1.05 V vs. Ag/AgCl (3 M KCl). The influence of most of the interferents present in real samples, supporting electrolyte and DPV parameters was investigated. A VB6 sensor with and linear range from 7 to 47 and a detection limit of 3.76 was obtain after optimization. Repeatability of the proposed procedure calculated after 7 measurements of 9 and 30 mu M of VB6 was 3.6 and 2.4%, respectively. Proposed methodology was successfully applied for the determination of VB6 in real samples, and from obtained results, it can be concluded that proposed analytical procedure can be an inexpensive alternative to the widely used separation methods. Prime Novelty statement: This work presents the quantification of vitam...in B-6, using differential pulse voltammetry, with boron-doped diamond electrode. BDD electrode is, up to date, one of the best electrode materials, with extremely low background current and negligible passivation. The aim of this study was to develop method for vitamin B-6 determination in various matrices, as can be seen from the results, the obtained procedure shows good recovery values in tested samples and could be a satisfactory replacement to the separation methods and modified electrodes. (C) 2016 Elsevier B.V. All rights reserved.
Кључне речи:
Parameters / Optimization / Real samples / DP voltammetryИзвор:
Diamond and Related Materials, 2016, 64, 184-189Издавач:
- Elsevier Science Sa, Lausanne
Финансирање / пројекти:
- Примена унапређених оксидационих процеса и наноструктурисаних оксидних материјала за уклањање загађивача из животне средине, развој и оптимизација инструменталних техника за праћење ефикасности (RS-MESTD-Basic Research (BR or ON)-172030)
- JoinEU-SEE-Penta Erasmus Mundus scholarship
Напомена:
- This is peer-reviewed version of the following article: Kuzmanović, D.; Khan, M.; Mehmeti, E.; Nazir, R.; Amaizah, N. R. R.; Stanković, D. Determination of Pyridoxine (Vitamin B-6) in Pharmaceuticals and Urine Samples Using Unmodified Boron-Doped Diamond Electrode. Diamond and Related Materials 2016, 64, 184–189. https://doi.org/10.1016/j.diamond.2016.02.018
DOI: 10.1016/j.diamond.2016.02.018
ISSN: 0925-9635
WoS: 000374608100023
Scopus: 2-s2.0-84959332031
Колекције
Институција/група
Inovacioni centar / Innovation CentreTY - JOUR AU - Kuzmanović, Darko AU - Khan, Muslim AU - Mehmeti, Eda AU - Nazir, Ruclia AU - Amaizah, Naser Ramdan R. AU - Stanković, Dalibor PY - 2016 UR - https://cherry.chem.bg.ac.rs/handle/123456789/3437 AB - Pyridoxine (vitamin B-6, VB6) was detected in pharmaceutical preparation and human urine samples by employing differential pulse voltammetry (DPV) at unmodified boron doped electrode. In Britton-Robinson buffer solution (BRBS) at pH 6, VB6 provides well defined oxidation peak at around +1.05 V vs. Ag/AgCl (3 M KCl). The influence of most of the interferents present in real samples, supporting electrolyte and DPV parameters was investigated. A VB6 sensor with and linear range from 7 to 47 and a detection limit of 3.76 was obtain after optimization. Repeatability of the proposed procedure calculated after 7 measurements of 9 and 30 mu M of VB6 was 3.6 and 2.4%, respectively. Proposed methodology was successfully applied for the determination of VB6 in real samples, and from obtained results, it can be concluded that proposed analytical procedure can be an inexpensive alternative to the widely used separation methods. Prime Novelty statement: This work presents the quantification of vitamin B-6, using differential pulse voltammetry, with boron-doped diamond electrode. BDD electrode is, up to date, one of the best electrode materials, with extremely low background current and negligible passivation. The aim of this study was to develop method for vitamin B-6 determination in various matrices, as can be seen from the results, the obtained procedure shows good recovery values in tested samples and could be a satisfactory replacement to the separation methods and modified electrodes. (C) 2016 Elsevier B.V. All rights reserved. PB - Elsevier Science Sa, Lausanne T2 - Diamond and Related Materials T1 - Determination of pyridoxine (vitamin B-6) in pharmaceuticals and urine samples using unmodified boron-doped diamond electrode VL - 64 SP - 184 EP - 189 DO - 10.1016/j.diamond.2016.02.018 ER -
@article{ author = "Kuzmanović, Darko and Khan, Muslim and Mehmeti, Eda and Nazir, Ruclia and Amaizah, Naser Ramdan R. and Stanković, Dalibor", year = "2016", abstract = "Pyridoxine (vitamin B-6, VB6) was detected in pharmaceutical preparation and human urine samples by employing differential pulse voltammetry (DPV) at unmodified boron doped electrode. In Britton-Robinson buffer solution (BRBS) at pH 6, VB6 provides well defined oxidation peak at around +1.05 V vs. Ag/AgCl (3 M KCl). The influence of most of the interferents present in real samples, supporting electrolyte and DPV parameters was investigated. A VB6 sensor with and linear range from 7 to 47 and a detection limit of 3.76 was obtain after optimization. Repeatability of the proposed procedure calculated after 7 measurements of 9 and 30 mu M of VB6 was 3.6 and 2.4%, respectively. Proposed methodology was successfully applied for the determination of VB6 in real samples, and from obtained results, it can be concluded that proposed analytical procedure can be an inexpensive alternative to the widely used separation methods. Prime Novelty statement: This work presents the quantification of vitamin B-6, using differential pulse voltammetry, with boron-doped diamond electrode. BDD electrode is, up to date, one of the best electrode materials, with extremely low background current and negligible passivation. The aim of this study was to develop method for vitamin B-6 determination in various matrices, as can be seen from the results, the obtained procedure shows good recovery values in tested samples and could be a satisfactory replacement to the separation methods and modified electrodes. (C) 2016 Elsevier B.V. All rights reserved.", publisher = "Elsevier Science Sa, Lausanne", journal = "Diamond and Related Materials", title = "Determination of pyridoxine (vitamin B-6) in pharmaceuticals and urine samples using unmodified boron-doped diamond electrode", volume = "64", pages = "184-189", doi = "10.1016/j.diamond.2016.02.018" }
Kuzmanović, D., Khan, M., Mehmeti, E., Nazir, R., Amaizah, N. R. R.,& Stanković, D.. (2016). Determination of pyridoxine (vitamin B-6) in pharmaceuticals and urine samples using unmodified boron-doped diamond electrode. in Diamond and Related Materials Elsevier Science Sa, Lausanne., 64, 184-189. https://doi.org/10.1016/j.diamond.2016.02.018
Kuzmanović D, Khan M, Mehmeti E, Nazir R, Amaizah NRR, Stanković D. Determination of pyridoxine (vitamin B-6) in pharmaceuticals and urine samples using unmodified boron-doped diamond electrode. in Diamond and Related Materials. 2016;64:184-189. doi:10.1016/j.diamond.2016.02.018 .
Kuzmanović, Darko, Khan, Muslim, Mehmeti, Eda, Nazir, Ruclia, Amaizah, Naser Ramdan R., Stanković, Dalibor, "Determination of pyridoxine (vitamin B-6) in pharmaceuticals and urine samples using unmodified boron-doped diamond electrode" in Diamond and Related Materials, 64 (2016):184-189, https://doi.org/10.1016/j.diamond.2016.02.018 . .