Salting-out thin-layer chromatography of some macrolide antibiotics
Апстракт
The chromatographic behavior of roxithromycin, midecamycin, erythromycin, azithromycin, and erythromycin ethylsuccinate has been studied by salting-out thin-layer chromatography (SOTLC) with cellulose as a adsorbent and aqueous ammonium sulfate solutions of different concentration as mobile phases. Hydrophobicity was determined from the linear relationships between solute R-M values and the ammonium sulfate content of the mobile phase. Hydrophobicity values R-M(0) and C-0 were calculated on the basis of the results obtained. Lipophilicity determined in this way was correlated with calculated log P values.
Кључне речи:
salting-out thin-layer chromatography (SOTLC) / macrolide antibiotics / cellulose / hydrophobicityИзвор:
Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography, 2005, 18, 106, 415-418Издавач:
- Research Inst Medicinal Plants, Budakalasz
DOI: 10.1556/JPC.18.2005.6.2
ISSN: 0933-4173
WoS: 000234495800002
Scopus: 2-s2.0-29644446646
Колекције
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Tosti, Tomislav AU - Drljevic, K AU - Milojković-Opsenica, Dušanka AU - Tešić, Živoslav Lj. PY - 2005 UR - https://cherry.chem.bg.ac.rs/handle/123456789/747 AB - The chromatographic behavior of roxithromycin, midecamycin, erythromycin, azithromycin, and erythromycin ethylsuccinate has been studied by salting-out thin-layer chromatography (SOTLC) with cellulose as a adsorbent and aqueous ammonium sulfate solutions of different concentration as mobile phases. Hydrophobicity was determined from the linear relationships between solute R-M values and the ammonium sulfate content of the mobile phase. Hydrophobicity values R-M(0) and C-0 were calculated on the basis of the results obtained. Lipophilicity determined in this way was correlated with calculated log P values. PB - Research Inst Medicinal Plants, Budakalasz T2 - Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography T1 - Salting-out thin-layer chromatography of some macrolide antibiotics VL - 18 IS - 106 SP - 415 EP - 418 DO - 10.1556/JPC.18.2005.6.2 ER -
@article{ author = "Tosti, Tomislav and Drljevic, K and Milojković-Opsenica, Dušanka and Tešić, Živoslav Lj.", year = "2005", abstract = "The chromatographic behavior of roxithromycin, midecamycin, erythromycin, azithromycin, and erythromycin ethylsuccinate has been studied by salting-out thin-layer chromatography (SOTLC) with cellulose as a adsorbent and aqueous ammonium sulfate solutions of different concentration as mobile phases. Hydrophobicity was determined from the linear relationships between solute R-M values and the ammonium sulfate content of the mobile phase. Hydrophobicity values R-M(0) and C-0 were calculated on the basis of the results obtained. Lipophilicity determined in this way was correlated with calculated log P values.", publisher = "Research Inst Medicinal Plants, Budakalasz", journal = "Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography", title = "Salting-out thin-layer chromatography of some macrolide antibiotics", volume = "18", number = "106", pages = "415-418", doi = "10.1556/JPC.18.2005.6.2" }
Tosti, T., Drljevic, K., Milojković-Opsenica, D.,& Tešić, Ž. Lj.. (2005). Salting-out thin-layer chromatography of some macrolide antibiotics. in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography Research Inst Medicinal Plants, Budakalasz., 18(106), 415-418. https://doi.org/10.1556/JPC.18.2005.6.2
Tosti T, Drljevic K, Milojković-Opsenica D, Tešić ŽL. Salting-out thin-layer chromatography of some macrolide antibiotics. in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography. 2005;18(106):415-418. doi:10.1556/JPC.18.2005.6.2 .
Tosti, Tomislav, Drljevic, K, Milojković-Opsenica, Dušanka, Tešić, Živoslav Lj., "Salting-out thin-layer chromatography of some macrolide antibiotics" in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography, 18, no. 106 (2005):415-418, https://doi.org/10.1556/JPC.18.2005.6.2 . .