XH/pi interactions with the pi system of porphyrin ring in porphyrin-containing proteins
Само за регистроване кориснике
2007
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Searching structures of porphyrin-containing proteins from the Protein Data Bank revealed that the pi system of every porphyrin ring is involved in XH/pi interactions, with most of the porphyrins having several interactions. Both five-membered pyrrole rings and six-membered chelate rings are involved in XH/pi interactions; the number of interactions with five-membered rings is larger than the number of interactions with six-membered rings. We found interactions with C-H and N-H groups as hydrogen-atom donors; however, the number of CH/pi interactions is much larger than the number of NH/pi interactions. The amino acids involved in the interactions show a high conservation score. Our results that every porphyrin is involved in XH/pi interactions and that amino acids involved in these interactions are highly conserved demonstrate that XH/pi interactions play an important role in porphyrin-protein stability.
Кључне речи:
XH/pi interactions / weak interactions / porphyrin / protein stability / conservation scoreИзвор:
Journal of Biological Inorganic Chemistry, 2007, 12, 7, 1063-1071Издавач:
- Springer, New York
Финансирање / пројекти:
- Проучавање односа реактивности, нековалентних интеракција и структуре молекула и моделовање хемијских система (RS-MESTD-MPN2006-2010-142037)
- Аутоматско резоновање и напредне обраде великих количина података и текста (RS-MESTD-MPN2006-2010-144030)
DOI: 10.1007/s00775-007-0276-0
ISSN: 0949-8257
PubMed: 17659366
WoS: 000249213800011
Scopus: 2-s2.0-34548445037
Колекције
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Stojanović, Srđan Đ. AU - Medaković, Vesna AU - Predovic, Goran AU - Beljanski, Milos AU - Zarić, Snežana D. PY - 2007 UR - https://cherry.chem.bg.ac.rs/handle/123456789/863 AB - Searching structures of porphyrin-containing proteins from the Protein Data Bank revealed that the pi system of every porphyrin ring is involved in XH/pi interactions, with most of the porphyrins having several interactions. Both five-membered pyrrole rings and six-membered chelate rings are involved in XH/pi interactions; the number of interactions with five-membered rings is larger than the number of interactions with six-membered rings. We found interactions with C-H and N-H groups as hydrogen-atom donors; however, the number of CH/pi interactions is much larger than the number of NH/pi interactions. The amino acids involved in the interactions show a high conservation score. Our results that every porphyrin is involved in XH/pi interactions and that amino acids involved in these interactions are highly conserved demonstrate that XH/pi interactions play an important role in porphyrin-protein stability. PB - Springer, New York T2 - Journal of Biological Inorganic Chemistry T1 - XH/pi interactions with the pi system of porphyrin ring in porphyrin-containing proteins VL - 12 IS - 7 SP - 1063 EP - 1071 DO - 10.1007/s00775-007-0276-0 ER -
@article{ author = "Stojanović, Srđan Đ. and Medaković, Vesna and Predovic, Goran and Beljanski, Milos and Zarić, Snežana D.", year = "2007", abstract = "Searching structures of porphyrin-containing proteins from the Protein Data Bank revealed that the pi system of every porphyrin ring is involved in XH/pi interactions, with most of the porphyrins having several interactions. Both five-membered pyrrole rings and six-membered chelate rings are involved in XH/pi interactions; the number of interactions with five-membered rings is larger than the number of interactions with six-membered rings. We found interactions with C-H and N-H groups as hydrogen-atom donors; however, the number of CH/pi interactions is much larger than the number of NH/pi interactions. The amino acids involved in the interactions show a high conservation score. Our results that every porphyrin is involved in XH/pi interactions and that amino acids involved in these interactions are highly conserved demonstrate that XH/pi interactions play an important role in porphyrin-protein stability.", publisher = "Springer, New York", journal = "Journal of Biological Inorganic Chemistry", title = "XH/pi interactions with the pi system of porphyrin ring in porphyrin-containing proteins", volume = "12", number = "7", pages = "1063-1071", doi = "10.1007/s00775-007-0276-0" }
Stojanović, S. Đ., Medaković, V., Predovic, G., Beljanski, M.,& Zarić, S. D.. (2007). XH/pi interactions with the pi system of porphyrin ring in porphyrin-containing proteins. in Journal of Biological Inorganic Chemistry Springer, New York., 12(7), 1063-1071. https://doi.org/10.1007/s00775-007-0276-0
Stojanović SĐ, Medaković V, Predovic G, Beljanski M, Zarić SD. XH/pi interactions with the pi system of porphyrin ring in porphyrin-containing proteins. in Journal of Biological Inorganic Chemistry. 2007;12(7):1063-1071. doi:10.1007/s00775-007-0276-0 .
Stojanović, Srđan Đ., Medaković, Vesna, Predovic, Goran, Beljanski, Milos, Zarić, Snežana D., "XH/pi interactions with the pi system of porphyrin ring in porphyrin-containing proteins" in Journal of Biological Inorganic Chemistry, 12, no. 7 (2007):1063-1071, https://doi.org/10.1007/s00775-007-0276-0 . .