Electrochemical Behavior and antioxidant and prooxidant activity of natural phenolics
Apstrakt
We have investigated the electrochemical oxidation of a number natural phenolics ( salicylic acid, m-hydroxybenzoic acid, p-hydroxybenzoic acid, protocatechuic acid, o-coumaric acid, m-coumaric acid, p-coumaric acid, caffeic acid, quercetin and rutin) using cyclic voltammetry. The antioxidant properties of these compounds were also studied. A structural analysis of the tested phenolics suggests that multiple OH substitution and conjugation are important determinants of the free radical scavenging activity and electrochemical behavior. Compounds with low oxidation potentials (Epa lower than 0.45) showed antioxidant activity, whereas compounds with high Epa values ( gt 0.45) act as prooxidants.
Ključne reči:
phenolics / cyclic voltammetry / antioxidant activity / prooxidant activityIzvor:
Molecules, 2007, 12, 10, 2327-2340Izdavač:
- Molecular Diversity Preservation Int, Basel
DOI: 10.3390/12102327
ISSN: 1420-3049
PubMed: 17978760
WoS: 000252173100006
Scopus: 2-s2.0-35949003260
Kolekcije
Institucija/grupa
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Simic, Aleksandra AU - Manojlović, Dragan D. AU - Šegan, Dejan M. AU - Todorović, Marija B. PY - 2007 UR - https://cherry.chem.bg.ac.rs/handle/123456789/898 AB - We have investigated the electrochemical oxidation of a number natural phenolics ( salicylic acid, m-hydroxybenzoic acid, p-hydroxybenzoic acid, protocatechuic acid, o-coumaric acid, m-coumaric acid, p-coumaric acid, caffeic acid, quercetin and rutin) using cyclic voltammetry. The antioxidant properties of these compounds were also studied. A structural analysis of the tested phenolics suggests that multiple OH substitution and conjugation are important determinants of the free radical scavenging activity and electrochemical behavior. Compounds with low oxidation potentials (Epa lower than 0.45) showed antioxidant activity, whereas compounds with high Epa values ( gt 0.45) act as prooxidants. PB - Molecular Diversity Preservation Int, Basel T2 - Molecules T1 - Electrochemical Behavior and antioxidant and prooxidant activity of natural phenolics VL - 12 IS - 10 SP - 2327 EP - 2340 DO - 10.3390/12102327 ER -
@article{ author = "Simic, Aleksandra and Manojlović, Dragan D. and Šegan, Dejan M. and Todorović, Marija B.", year = "2007", abstract = "We have investigated the electrochemical oxidation of a number natural phenolics ( salicylic acid, m-hydroxybenzoic acid, p-hydroxybenzoic acid, protocatechuic acid, o-coumaric acid, m-coumaric acid, p-coumaric acid, caffeic acid, quercetin and rutin) using cyclic voltammetry. The antioxidant properties of these compounds were also studied. A structural analysis of the tested phenolics suggests that multiple OH substitution and conjugation are important determinants of the free radical scavenging activity and electrochemical behavior. Compounds with low oxidation potentials (Epa lower than 0.45) showed antioxidant activity, whereas compounds with high Epa values ( gt 0.45) act as prooxidants.", publisher = "Molecular Diversity Preservation Int, Basel", journal = "Molecules", title = "Electrochemical Behavior and antioxidant and prooxidant activity of natural phenolics", volume = "12", number = "10", pages = "2327-2340", doi = "10.3390/12102327" }
Simic, A., Manojlović, D. D., Šegan, D. M.,& Todorović, M. B.. (2007). Electrochemical Behavior and antioxidant and prooxidant activity of natural phenolics. in Molecules Molecular Diversity Preservation Int, Basel., 12(10), 2327-2340. https://doi.org/10.3390/12102327
Simic A, Manojlović DD, Šegan DM, Todorović MB. Electrochemical Behavior and antioxidant and prooxidant activity of natural phenolics. in Molecules. 2007;12(10):2327-2340. doi:10.3390/12102327 .
Simic, Aleksandra, Manojlović, Dragan D., Šegan, Dejan M., Todorović, Marija B., "Electrochemical Behavior and antioxidant and prooxidant activity of natural phenolics" in Molecules, 12, no. 10 (2007):2327-2340, https://doi.org/10.3390/12102327 . .