TY  - THES
AU  - Berbić, Damir
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5451
AB  - Amiloidni fibrili predstavljaju termodinamički najstabilnije konformacije proteina. Mehanizam njihovog nastanka opisan je teorijom uvijanja proteina prikazanom preko reljefa energetskog levka. Nagomilavanje amiloidnih fibrila u organizmu uzrok je patoloških promena poput Alchajmerove bolesti, Parkinsonove bolesti, Hantingtonove boleste i drugih sistemskih i lokalnih amiloidoza. Usled specifične strukture, amiloidni fibrili se mogu uspešno primeniti za pravljenje biokompatibilnih nanomaterijala, ambalaže hrane, nosača terapeutika. Iz navedenih razloga, dobijanje amiloidnih fibrila na većoj skali je od velike važnosti za nastavak proučavanja primene amiloida u naukama o materijalima. U ovom radu je optimizovan proces formiranja amiloidnih fibrila na velikoj skali. Proces fibrilacije je praćen spektrofluorimetrijom dok je nestanak ovalbumina, model sistema, praćen elektroforetskim metodoma. Optimizovano je vreme same inkubacije.
T1  - Optimizacija postupka formiranja amiloidnih fibrila na velikoj skali
SP  - 1
EP  - 27
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5451
ER  - 

@misc{
author = "Berbić, Damir",
year = "2022",
abstract = "Amiloidni fibrili predstavljaju termodinamički najstabilnije konformacije proteina. Mehanizam njihovog nastanka opisan je teorijom uvijanja proteina prikazanom preko reljefa energetskog levka. Nagomilavanje amiloidnih fibrila u organizmu uzrok je patoloških promena poput Alchajmerove bolesti, Parkinsonove bolesti, Hantingtonove boleste i drugih sistemskih i lokalnih amiloidoza. Usled specifične strukture, amiloidni fibrili se mogu uspešno primeniti za pravljenje biokompatibilnih nanomaterijala, ambalaže hrane, nosača terapeutika. Iz navedenih razloga, dobijanje amiloidnih fibrila na većoj skali je od velike važnosti za nastavak proučavanja primene amiloida u naukama o materijalima. U ovom radu je optimizovan proces formiranja amiloidnih fibrila na velikoj skali. Proces fibrilacije je praćen spektrofluorimetrijom dok je nestanak ovalbumina, model sistema, praćen elektroforetskim metodoma. Optimizovano je vreme same inkubacije.",
title = "Optimizacija postupka formiranja amiloidnih fibrila na velikoj skali",
pages = "1-27",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5451"
}

Berbić, D.. (2022). Optimizacija postupka formiranja amiloidnih fibrila na velikoj skali. , 1-27.
https://hdl.handle.net/21.15107/rcub_cherry_5451

Berbić D. Optimizacija postupka formiranja amiloidnih fibrila na velikoj skali. 2022;:1-27.
https://hdl.handle.net/21.15107/rcub_cherry_5451 .

Berbić, Damir, "Optimizacija postupka formiranja amiloidnih fibrila na velikoj skali" (2022):1-27,
https://hdl.handle.net/21.15107/rcub_cherry_5451 .

TY  - CONF
AU  - Berbić, Damir
AU  - Araškov, Jovana
AU  - Filipović, Nenad
AU  - Todorović, Tamara
PY  - 2019
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6000
AB  - New nickel(II) complex with (E)-4-(4-tolylphenyl)-2-(2-(2-pyridylmethyilidene)hydrazinyl)thiazole (HL) was synthesized and characterized. The complex was synthesized by the reaction of the ligand with nickel(II) perchlorate hexahydrate and obtained in a single crystal form. The structure of the complex, with general formula [NiL2](ClO4)2, was solved by a single crystal X-ray diffraction analysis (Fig. 1). HL is tridentately coordinated to nickel(II) via pyridine, imine and thiazole nitrogen atoms with two perchlorate anions in the outer sphere. Besides electrostatic interactions, hydrogen interactions are also present in the crystal packing of the complex. Magnetic moment and conductivity measurements showed that the complex is paramagnetic and 2 : 1 type of electrolyte.

Antiproliferative activity of the complex was evaluated against several human tumour cell lines. The complex showed better activity than positive control 
5-fluorouracil. The complex was shown to highly efficiently catalyze photodegradation of reactive Orange 16 dye.
PB  - Belgrade : Serbian Chemical Society
C3  - Seventh Conference of Young Chemists of Serbia, Belgrade, 2nd November 2019
T1  - Nickel(II) complex with hydrazinyl-thiazole: structural charactacterization, antiproliferative and photocatalytic activity
UR  - https://hdl.handle.net/21.15107/rcub_cherry_6000
ER  - 

@conference{
author = "Berbić, Damir and Araškov, Jovana and Filipović, Nenad and Todorović, Tamara",
year = "2019",
abstract = "New nickel(II) complex with (E)-4-(4-tolylphenyl)-2-(2-(2-pyridylmethyilidene)hydrazinyl)thiazole (HL) was synthesized and characterized. The complex was synthesized by the reaction of the ligand with nickel(II) perchlorate hexahydrate and obtained in a single crystal form. The structure of the complex, with general formula [NiL2](ClO4)2, was solved by a single crystal X-ray diffraction analysis (Fig. 1). HL is tridentately coordinated to nickel(II) via pyridine, imine and thiazole nitrogen atoms with two perchlorate anions in the outer sphere. Besides electrostatic interactions, hydrogen interactions are also present in the crystal packing of the complex. Magnetic moment and conductivity measurements showed that the complex is paramagnetic and 2 : 1 type of electrolyte.

Antiproliferative activity of the complex was evaluated against several human tumour cell lines. The complex showed better activity than positive control 
5-fluorouracil. The complex was shown to highly efficiently catalyze photodegradation of reactive Orange 16 dye.",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Seventh Conference of Young Chemists of Serbia, Belgrade, 2nd November 2019",
title = "Nickel(II) complex with hydrazinyl-thiazole: structural charactacterization, antiproliferative and photocatalytic activity",
url = "https://hdl.handle.net/21.15107/rcub_cherry_6000"
}

Berbić, D., Araškov, J., Filipović, N.,& Todorović, T.. (2019). Nickel(II) complex with hydrazinyl-thiazole: structural charactacterization, antiproliferative and photocatalytic activity. in Seventh Conference of Young Chemists of Serbia, Belgrade, 2nd November 2019
Belgrade : Serbian Chemical Society..
https://hdl.handle.net/21.15107/rcub_cherry_6000

Berbić D, Araškov J, Filipović N, Todorović T. Nickel(II) complex with hydrazinyl-thiazole: structural charactacterization, antiproliferative and photocatalytic activity. in Seventh Conference of Young Chemists of Serbia, Belgrade, 2nd November 2019. 2019;.
https://hdl.handle.net/21.15107/rcub_cherry_6000 .

Berbić, Damir, Araškov, Jovana, Filipović, Nenad, Todorović, Tamara, "Nickel(II) complex with hydrazinyl-thiazole: structural charactacterization, antiproliferative and photocatalytic activity" in Seventh Conference of Young Chemists of Serbia, Belgrade, 2nd November 2019 (2019),
https://hdl.handle.net/21.15107/rcub_cherry_6000 .