TY  - JOUR
AU  - Vitomirov, Teodora
AU  - Čobeljić, Božidar
AU  - Pevec, Andrej
AU  - Radanović, Dušanka
AU  - Novaković, Irena T.
AU  - Savić, Milica
AU  - Anđelković, Katarina K.
AU  - Ristović, Maja Šumar
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6387
AB  - The condensation product of 7-acetyl-6-azaindole and Girard’s T reagent ((E)-2-(2-(1-(1H-pyrrolo[2,3-c]pyridin-7-yl)ethylidene)hydrazineyl)-N,N,N-trimethyl-2-oxoethan-1-aminium, HL ligand) was used as a ligand in the reaction with Cu(BF4)2·6H2O and NaN3. The reaction led to the formation of a binuclear Cu(II) complex containing two end-to-end (di-m-1,3-N3) azide bridges, as well as two NNO-donor hydrazone ligands, forming an axially elongated square pyramidal geometry around each Cu(II) center. This end-to-end (di-m-1,3-N3) azide bridge binding mode has not yet been reported, in Cu(II) complexes containing the NNO-donor hydrazone ligands, which makes the structure of the complex even more interesting for further studies. The com­plex was characterized by elemental analysis, IR spectroscopy and X-ray crys­tal­lography, and it was found that it crystallizes in the triclinic space group P–1 with the asymmetric unit comprising one Cu(II) centre, zwitterionic ligand L, one azide (N3-) ligand and BF4- counter anion. Examination of antimicrobial activity of the complex shows higher antifungal and antibacterial activity towards tested Gram-positive bacteria in comparison to the hydrazone ligand, with the antifungal activity of the complex even being comparable to the act­ivity of amphotericin B.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Binuclear azide-bridged hydrazone Cu(II) complex: Synthesis, characterization and evaluation of biological activity: Scientific paper
VL  - 88
IS  - 9
SP  - 877
EP  - 888
DO  - 10.2298/JSC230623044V
ER  - 

@article{
author = "Vitomirov, Teodora and Čobeljić, Božidar and Pevec, Andrej and Radanović, Dušanka and Novaković, Irena T. and Savić, Milica and Anđelković, Katarina K. and Ristović, Maja Šumar",
year = "2023",
abstract = "The condensation product of 7-acetyl-6-azaindole and Girard’s T reagent ((E)-2-(2-(1-(1H-pyrrolo[2,3-c]pyridin-7-yl)ethylidene)hydrazineyl)-N,N,N-trimethyl-2-oxoethan-1-aminium, HL ligand) was used as a ligand in the reaction with Cu(BF4)2·6H2O and NaN3. The reaction led to the formation of a binuclear Cu(II) complex containing two end-to-end (di-m-1,3-N3) azide bridges, as well as two NNO-donor hydrazone ligands, forming an axially elongated square pyramidal geometry around each Cu(II) center. This end-to-end (di-m-1,3-N3) azide bridge binding mode has not yet been reported, in Cu(II) complexes containing the NNO-donor hydrazone ligands, which makes the structure of the complex even more interesting for further studies. The com­plex was characterized by elemental analysis, IR spectroscopy and X-ray crys­tal­lography, and it was found that it crystallizes in the triclinic space group P–1 with the asymmetric unit comprising one Cu(II) centre, zwitterionic ligand L, one azide (N3-) ligand and BF4- counter anion. Examination of antimicrobial activity of the complex shows higher antifungal and antibacterial activity towards tested Gram-positive bacteria in comparison to the hydrazone ligand, with the antifungal activity of the complex even being comparable to the act­ivity of amphotericin B.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Binuclear azide-bridged hydrazone Cu(II) complex: Synthesis, characterization and evaluation of biological activity: Scientific paper",
volume = "88",
number = "9",
pages = "877-888",
doi = "10.2298/JSC230623044V"
}

Vitomirov, T., Čobeljić, B., Pevec, A., Radanović, D., Novaković, I. T., Savić, M., Anđelković, K. K.,& Ristović, M. Š.. (2023). Binuclear azide-bridged hydrazone Cu(II) complex: Synthesis, characterization and evaluation of biological activity: Scientific paper. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 88(9), 877-888.
https://doi.org/10.2298/JSC230623044V

Vitomirov T, Čobeljić B, Pevec A, Radanović D, Novaković IT, Savić M, Anđelković KK, Ristović MŠ. Binuclear azide-bridged hydrazone Cu(II) complex: Synthesis, characterization and evaluation of biological activity: Scientific paper. in Journal of the Serbian Chemical Society. 2023;88(9):877-888.
doi:10.2298/JSC230623044V .

Vitomirov, Teodora, Čobeljić, Božidar, Pevec, Andrej, Radanović, Dušanka, Novaković, Irena T., Savić, Milica, Anđelković, Katarina K., Ristović, Maja Šumar, "Binuclear azide-bridged hydrazone Cu(II) complex: Synthesis, characterization and evaluation of biological activity: Scientific paper" in Journal of the Serbian Chemical Society, 88, no. 9 (2023):877-888,
https://doi.org/10.2298/JSC230623044V . .