Претраживање
Приказ резултата 1-10 од 1214
Conserved Structural Motif for Recognizing Nicotinamide Adenine Dinucleotide in Poly(ADP-ribose) Polymerases and ADP-Ribosylating Toxins: Implications for Structure-Based Drug Design
(Amer Chemical Soc, Washington, 2010)
The ADP-ribosylating toxins (ADPRTs) and poly(ADP-ribose) polymerases (PARPs) are two important drug target protein families. Although the Y-X(10)-Y motif for the diphtheria toxin group and the STS motif for the other ...
2-Alkylidene-4-oxothiazolidine S-oxides: synthesis and stereochemistry
(Pergamon-Elsevier Science Ltd, Oxford, 2013)
A series of 5-unsubstituted and 5-substituted 2-alkylidene-4-oxothiazolidine-S-oxides were synthesized by the sulfur-oxidation with m-CPBA. The stereochemistry of 5-substituted sulfoxides was determined by means of NMR ...
Design of coiled-coil protein-origami cages that self-assemble in vitro and in vivo
(Nature Publishing Group, New York, 2017)
Polypeptides and polynucleotides are natural programmable biopolymers that can self-assemble into complex tertiary structures. We describe a system analogous to designed DNA nanostructures in which protein coiled-coil (CC) ...
Synthesis, Cytotoxic Activity, and Thermal Studies of Novel N-[(1,3-Diphenylpyrazol-4-yl)methyl] alpha-Amino Acids
(Wiley-Blackwell, Malden, 2010)
New N-[(1,3-diphenylpyrazol-4-yl)methyl]alpha-amino acids (1a-i) have been synthesized and tested in vitro for their antiproliferative activity against human myelogenous leukemia K562, colon adenocarcinoma HT-29, cervix ...
Insights into proteolytic processing of the major peanut allergen Ara h 2 by endogenous peanut proteases
(John Wiley & Sons Ltd, Chichester, 2010)
BACKGROUND: The major peanut allergens are Ara h 1, Ara h 2 and Ara h 6. Proteolytic processing has been shown to be required for the maturation process of Ara h 6. The aim of this study was to examine whether Ara h 2 ...
New potentiometric sensor for copper determination in waste waters based on a new type of modified GC electrode
(Analytical and Bioanalytical Chemistry, 2012)
The potentiometrical analysis of Cu2+ using Nafion- modified electrode with Cu complex with DPABA (Methyl 3,5-bis{bis-[(pyridin-2-yl)methyl]amino}methyl)benzoate) incorporated, is described. Parameters and conditions such ...
Yeast surface display for the expression, purification and characterization of wild-type and B11 mutant glucose oxidases
(Academic Press Inc Elsevier Science, San Diego, 2013)
Glucose oxidase (GOx) catalyzes the oxidation of glucose to form gluconic acid and hydrogen peroxide, a reaction with important applications in food preservation, the manufacture of cosmetics and pharmaceuticals, and the ...
Possible Sources of Heavy Metals in Urban Soils: Example from Belgrade, Serbia
(Scibulcom Ltd, Sofia, 2010)
The content of heavy metals over time has been continuously increasing in urban soils as a consequence of industrialisation and often unclear sets of environmental controls and protection procedures. However, the role of ...
DFT and MM description of the structure and magnetic properties of manganese complexes with X-phenylcyanamido bridging ligand
(Springer Wien, Wien, 2011)
Magnetic properties of the complexes [Mn(3-Clpcyd)(H(2)O)-(phen)(2)](+), [{Mn(3-Fpcyd)(MeOH)(phen)}(2)(mu-3-Fpcyd)(2)], [{Mn(3-Fpcyd)(EtOH)(phen)}(2)(mu-3-Fpcyd)(2)], [{Mn(3-Clpcyd)(MeOH)(phen)}(2)(mu-3-Clpcyd)(2)], and ...
Computational analysis of tris(1,2-ethanediamine) cobalt(III) complex ion: calculation of the Co-59 shielding tensor using LF-DFT
(Springer Wien, Wien, 2011)
The ligand-field density functional theory (LF-DFT) approach is employed for calculations of the Co-59 nuclear magnetic resonance (NMR) shielding tensor of all four diastereoisomers (lambda lambda lambda, lambda lambda I ...