Претраживање
Приказ резултата 1-2 од 2
Steric interactions and the activity of fentanyl analogs at the mu-opioid receptor
(Pergamon-Elsevier Science Ltd, Oxford, 2006)
Fentanyl is a highly potent and clinically widely used narcotic analgesic. The synthesis of its analogs remains a challenge in the attempt to develop highly selective p-opioid receptor agonists with specific pharmacological ...
Interaction of arylpiperazine ligands with the hydrophobic part of the 5-HT1A receptor binding site
(Pergamon-Elsevier Science Ltd, Oxford, 2006)
A flexible docking of a series of arylpiperazine derivatives with structurally different aryl part to the binding site of a model of human 5-HT1A receptor was exercised. The influence of structure and hydrophobic properties ...