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Interaction of arylpiperazine ligands with the hydrophobic part of the 5-HT1A receptor binding site
(Pergamon-Elsevier Science Ltd, Oxford, 2006)
A flexible docking of a series of arylpiperazine derivatives with structurally different aryl part to the binding site of a model of human 5-HT1A receptor was exercised. The influence of structure and hydrophobic properties ...
Influence of N-1 substituent properties on binding affinities of arylpiperazines to the binding site of 5-HT1A receptor / Uticaj osobina N-1 supstituenta na afinitet arilpiperazina prema vezivnom mestu 5-HT1A receptora
(Serbian Chemical Soc, Belgrade, 2006)
Scrotonin receptors (5-HTRs), especially the 5-HT1A subtype, have been the subject of intensive research for the past decade, due to their function in human physiology. Several structurally different classes of ligands are ...