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dc.creatorCubells-Baeza, N.
dc.creatorVerhoeckx, K.C.M.
dc.creatorLarre, C.
dc.creatorDenery-Papini, Sandra
dc.creatorGavrović-Jankulović, Marija
dc.creatorDiaz Perales, A.
dc.date.accessioned2018-11-22T00:30:23Z
dc.date.available2018-11-22T00:30:23Z
dc.date.issued2015
dc.identifier.issn1740-6757
dc.identifier.urihttp://cherry.chem.bg.ac.rs/handle/123456789/304
dc.description.abstractMeasurement of protein transport across the intestinal barrier might be a relevant approach in allergenicity risk assessment. Traditionally, studies on protein transport, were performed using stable cell lines cultured as a monolayer. One of the major advantages of these models is their relatively low price and easy handling. However, monolayers lack a physiologically relevant environment (presence of other cell-types and a mucus layer), which may have an effect on transport characteristics and thus correct prediction of protein allergenicity. This paper summarizes the most widely used epithelial models and discusses their benefits and limitations for measuring protein transport and allergic sensitization to food. © 2016 Elsevier Ltden
dc.rightsrestrictedAccess
dc.sourceDrug Discovery Today: Disease Models
dc.titleApplicability of epithelial models in protein permeability/transport studies and food allergyen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractДиаз Пералес, A.; Денерy-Папини, С.; Ларре, Ц.; Гавровић-Јанкуловић, Марија; Верхоецкx, К.Ц.М.; Цубеллс-Баеза, Н.;
dc.citation.spage13
dc.citation.epage21
dc.identifier.doi10.1016/j.ddmod.2016.08.002
dc.citation.other: 13-21
dc.type.versionpublishedVersionen
dc.identifier.scopus2-s2.0-85006253705
dc.identifier.rcubKon_1267


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