The synthesis and biological evaluation of 3β-hydroxylanosta-7,9-dien-32-al

dc.creator	Šolaja, Bogdan A.
dc.creator	Djermanović, M.
dc.creator	Lim, D.M.
dc.creator	Paik, Y.-K.
dc.date.accessioned	2018-11-22T00:01:07Z
dc.date.available	2018-11-22T00:01:07Z
dc.date.issued	1996
dc.identifier.issn	0352-5139
dc.identifier.uri	https://cherry.chem.bg.ac.rs/handle/123456789/97
dc.description.abstract	The synthesis of the title compound a key intermediate for the synthesis of other DHL derivatives, is reported. The aldehyde 1 and the diol 9 were tested on several enzymes involved in the cholesterol biosynthetic pathway. Aldehyde 1 showed an inhibitory effect IC50 = 90 μM on sterol 14-reductase.	en
dc.rights	restrictedAccess
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.source	Journal of the Serbian Chemical Society
dc.subject	Dihydrolanosterol Δ7,9 derivatives	en
dc.subject	Enzyme inhibitory effect of	en
dc.subject	Synthesis	en
dc.title	The synthesis and biological evaluation of 3β-hydroxylanosta-7,9-dien-32-al	en
dc.type	article
dc.rights.license	BY-NC-ND
dc.citation.volume	61
dc.citation.issue	11
dc.citation.spage	1113
dc.citation.epage	1116
dc.citation.other	61(11): 1113-1116
dc.type.version	publishedVersion	en
dc.identifier.scopus	2-s2.0-4244175165
dc.identifier.rcub	https://hdl.handle.net/21.15107/rcub_cherry_97

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