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New radical reactions of S-alkoxycarbonyl xanthates. Total synthesis of (+/-)-cinnamolide and (+/-)-metlhylenolactocin
(Pergamon-Elsevier Science Ltd, Oxford, 1999)
Irradiation with visible light of S-alkoxycarbonyl xanthates derived from various alcohols gives rise to alkoxycarbonyl radicals with bifurcate reactivity: loss of carbon dioxide leads to deoxygenated derivatives (i.e. ...
Protecting group-free syntheses of natural products and biologically active compounds (vol 70, pg 8183, 2014)
(Pergamon-Elsevier Science Ltd, Oxford, 2015)
Synthesis and properties of bis(pyrrolidino)fullerenes bridged by a flexible alkyl-tether
(Pergamon-Elsevier Science Ltd, Oxford, 2015)
The one-pot bistycloaddition of alkyl-tethered diglycines to C-60 provided five series of bridged bis(pyrrolidino)fullerenes with good regioselectivity, giving mainly cis-2 and cis-3 products. An influence of the bridge ...
Exploring the biocatalytic potential of a DyP-type peroxidase by profiling the substrate acceptance of Thermobifida fusca DyP peroxidase
(Pergamon-Elsevier Science Ltd, Oxford, 2016)
Dye-decolorizing peroxidases (DyPs) represent a new class of oxidative enzymes for which the natural substrates are largely unknown. To explore the biocatalytic potential of a DyP, we have studied the substrate acceptance ...
Design, synthesis, and characterization of fullerene-peptide-steroid covalent hybrids
(Pergamon-Elsevier Science Ltd, Oxford, 2014)
The present study reports the synthesis, spectral characterization, self-assembly properties, and preliminary in vitro study of antioxidant capacity of two triple covalent hybrids consisting of fullerene C-60, peptide, and ...
Oxidative 10-membered ring expansion and contraction of stereoisomeric 1(10)-unsaturated and 1,10-epoxy-5-oxo-5,10-secosteroids induced by peracids
(Pergamon-Elsevier Science Ltd, Oxford, 2012)
The present study is concerned with the oxidative behaviour of unsaturated and epoxy 5-oxo-5,10-secosteroids in the presence of m-CPBA or TFAA-UHP as oxidants in order to investigate potential parameters controlling the ...
Organocatalyzed synthesis of (-)-4-epi-fagomine and the corresponding pipecolic acids
(Pergamon-Elsevier Science Ltd, Oxford, 2015)
The enantioselective synthesis of 4-epi-fagomine was accomplished starting from dioxanone and Cbz-protected benyzlamine, in 4 steps, with 18% overall yield. The key feature of this synthetic approach is the tactical ...
A short stereoselective synthesis of (+)-aza-galacto-fagomine (AGF)
(Pergamon-Elsevier Science Ltd, Oxford, 2017)
A catalytic asymmetric synthesis of (+)-aza-galacto-fagomine (AGF) - the most promising compound for the pharmacological chaperone therapy of Krabbe disease was accomplished in six steps, in 14% overall yield. The synthesis ...
Fullerene bisadduct regioisomers containing an asymmetric diamide tether
(Pergamon-Elsevier Science Ltd, Oxford, 2017)
Four macrocyclic bis(pyrrolidino)fullerene regioisomers with e-edge, e-face, trans-4 and cis-2 addition patterns were synthesized from the corresponding monoadduct by Prato's cycloaddition in a yield of 50%, and fully ...
Synthesis, biology, and modeling of a C-4 carbonyl C,D-seco-taxoid
(Pergamon-Elsevier Science Ltd, Oxford, 2006)
A C,D-seco-paclitaxel derivative 26 was prepared from taxine and tested for biological activity. Chemical reactivity of the seco-compounds proved to be substantially modified, with respects to taxoids. The corresponding ...