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dc.creatorPavlović, M.
dc.creatorDimitrijevic, A.
dc.creatorTrbojević-Ivić, Jovana
dc.creatorMilosavic, N.
dc.creatorGavrović-Jankulović, Marija
dc.creatorBezbradica, D.
dc.creatorVelickovic, D.
dc.date.accessioned2018-11-22T00:24:28Z
dc.date.available2018-11-22T00:24:28Z
dc.date.issued2013
dc.identifier.issn0036-0244
dc.identifier.urihttp://cherry.chem.bg.ac.rs/handle/123456789/1432
dc.description.abstractalpha-1,4-Glucosidase from Saccharomyces cerevisiae is an enzyme which is widely used in synthesis of different drugs. Glucosidase inhibitors are studied as potential drugs for prevention of HIV and diabetes. For understanding of these processes it is very important to have insights in the transglucosylation activity of this enzyme. In this paper the kinetics of transglucosylation reaction catalyzed by this enzyme in the synthesis of benzyl alcohol glucoside was studied and all relevant kinetic constants for this system are found. It was shown one additional property of transglycosylation reactions catalyzed by glycosidases-inhibition by both, glucose acceptor and glucose donor, and mechanisms for these inhibitions were proposed.en
dc.publisherMaik Nauka/Interperiodica/Springer, New York
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172049/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/46010/RS//
dc.relationinfo:eu-repo/grantAgreement/EC/FP7/256716/EU//
dc.rightsrestrictedAccess
dc.sourceRussian Journal of Physical Chemistry A
dc.subjectalpha-glucosidaseen
dc.subjecttransglucosylationen
dc.subjectbenzyl alcohol glucosideen
dc.subjectsubstrate inhibitionen
dc.subjectping-pong mechanisamen
dc.titleA study of transglucosylation kinetic in an enzymatic synthesis of benzyl alcohol glucoside by alpha-glucosidase from S-cerevisiaeen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractМилосавиц, Н.; Павловиц, М.; Гавровић-Јанкуловић, Марија; Трбојевић-Ивић, Јована; Димитријевиц, A.; Велицковиц, Д.; Безбрадица, Д.;
dc.citation.volume87
dc.citation.issue13
dc.citation.spage2285
dc.citation.epage2288
dc.identifier.wos000326718200028
dc.identifier.doi10.1134/S0036024413130207
dc.citation.other87(13): 2285-2288
dc.citation.rankM23
dc.type.versionpublishedVersionen
dc.identifier.scopus2-s2.0-84888146485
dc.identifier.rcubKon_2552


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Приказ основних података о документу