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Antiproliferative activity and QSAR studies of a series of new 4-aminomethylidene derivatives of some pyrazol-5-ones
(Pergamon-Elsevier Science Ltd, Oxford, 2011)
Twenty five 4-aminomethylidene derivatives obtained from 3-phenyl-2-pyrazolin-5-one and 1,3-diphenyl-2-pyrazolin-5-one were synthesized and tested for their antiproliferative activity against human breast cancer MDA-MB-361 ...
Pharmacological evaluation of 3-carbomethoxy fentanyl in mice
(Pharmaceuticals, 2011)
In many animal species, as well as in humans, high doses of fentanyl (F) produce marked neurotoxic effects, such as muscular rigidity and respiratory depression. The antinociception (hot-plate test), impairment of motor ...
NF-kappa B DNA binding activity of sesquiterpene lactones from Anthemis arvensis and Anthemis cotula
(Taylor & Francis Ltd, Abingdon, 2011)
Previous investigations of Anthemis arvensis L. and Anthemis cotula L., species growing wild in Serbia, revealed linear sesquiterpene lactones (SLs) with unusual types of skeleton, named antheindurolides and anthecotuloides. ...
Optimisation of high-quality nucleic acid isolation from linden tree (Tilia cordata) leaves and pollen
(Wiley-Blackwell, Hoboken, 2011)
An aldol approach to the enantioselective synthesis of (-)-oseltamivir phosphate
(Royal Soc Chemistry, Cambridge, 2011)
A formal asymmetric synthesis of the antiviral agent (-)-oseltamivir phosphate is achieved using two aldol reactions as key steps.
Complexation of amidated pectin with poly(itaconic acid) as a polycarboxylic polymer model compound
(Elsevier Sci Ltd, Oxford, 2011)
Complexes based on amidated pectin (AP) and poly(itaconic acid) (PIA) were prepared by casting films from solutions of AP and PIA in different ratios with the pectin amount ranging from 10% to 90% by mass. The complexes ...
Cell wall invertase immobilisation within gelatin gel
(Elsevier Sci Ltd, Oxford, 2011)
Yeast cell wall invertase (CWI) was immobilised within 10% gelatin hydrogel. The result of entrapment was the complete immobilisation of all the added CWI. The activity of immobilised biocatalyst was 93 +/- 3 U/g, with ...
Isolation and identification of phenolic compounds from Hypericum richeri Vill. and their antioxidant capacity
(Taylor & Francis Ltd, Abingdon, 2011)
The chemical composition and free radical scavenging properties of the MeOH extract of Hypericum richeri and its subsequent CHCl3, n-BuOH, EtOAc and aqueous extracts were investigated. Four quercetin-3-O-glycosides, three ...
A Useful Synthetic Equivalent of a Hydroxyacetone Enolate
(Amer Chemical Soc, Washington, 2011)
Indium promoted allyiation of carbonyl compounds with 4-(bromomethyl)-1,3-dioxol-2-one diastereoselectively affords and-alpha,beta-dihydroxyketones, protected as enol carbonates. These initial products can be deprotected ...
Synthesis, structural and spectroscopic characterization, in vitro cytotoxicity and in vivo activity as free radical scavengers of chlorido(p-cymene) complexes of ruthenium(II) containing N-alkylphenothiazines
(Elsevier France-Editions Scientifiques Medicales Elsevier, Paris, 2011)
Three new ruthenium(II) complexes 1-3 containing N-alkylphenothiazine molecules were synthesized by reaction of [RuCl2(eta(6)-P-cymene)](2) with chlorpromazine hydrochloride (1), trifluoperazine dihydrochloride (2) or ...