An approximate linear solvation energy relationships model based on Snyder's selectivity parameters. Chromatographic behavior of some 1-aralkyl-4-arylpiperazines
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2008
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Prikaz svih podataka o dokumentuApstrakt
In order to elucidate the influence of the mobile phase composition on the retention of some 1-aralkyl-4-arylpiperazines, Snyder's selectivity and polarity concept for building a simple linear solvation energy relationships model of chromatographic behavior was used. Maximum variability of mobile phase selectivity was achieved by using ternary mixtures of solvents from three different corners of the Snyder selectivity triangle: methanol as a strong proton donor, acetone as a strong proton acceptor and dimethyl formamide as a dipole interactor. Water was added to keep elution strength constant. Mobile phase composition was varied using Simplex-lattice mixture design. Selectivity parameters were calculated on the basis of linear relationships between volume fractions of pure solvents and their chi (e) , chi (d) , chi (n) values. For seven-substituted 1-aralkyl-4-arylpiperazines R (M) values were measured and correlated with previously calculated selectivity parameters. Mathematical model...s obtained are discussed according to the structural properties of the studied compounds.
Ključne reči:
thin-layer chromatography / arylpiperazines / linear solvation energy relationships / Snyder's selectivity parameter / polarity indexIzvor:
Chromatographia, 2008, 68, 5-6, 453-458Izdavač:
- Springer Heidelberg, Heidelberg
Finansiranje / projekti:
- Sinteza, analiza i aktivnost novih organskih polidentatnih liganada i njihovih kompleksa sa d-metalima (RS-MESTD-MPN2006-2010-142062)
DOI: 10.1365/s10337-008-0711-6
ISSN: 0009-5893
WoS: 000259186700023
Scopus: 2-s2.0-51849168917
Kolekcije
Institucija/grupa
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Andrić, Filip AU - Trifković, Jelena AU - Tešić, Živoslav Lj. AU - Milojković-Opsenica, Dušanka PY - 2008 UR - https://cherry.chem.bg.ac.rs/handle/123456789/971 AB - In order to elucidate the influence of the mobile phase composition on the retention of some 1-aralkyl-4-arylpiperazines, Snyder's selectivity and polarity concept for building a simple linear solvation energy relationships model of chromatographic behavior was used. Maximum variability of mobile phase selectivity was achieved by using ternary mixtures of solvents from three different corners of the Snyder selectivity triangle: methanol as a strong proton donor, acetone as a strong proton acceptor and dimethyl formamide as a dipole interactor. Water was added to keep elution strength constant. Mobile phase composition was varied using Simplex-lattice mixture design. Selectivity parameters were calculated on the basis of linear relationships between volume fractions of pure solvents and their chi (e) , chi (d) , chi (n) values. For seven-substituted 1-aralkyl-4-arylpiperazines R (M) values were measured and correlated with previously calculated selectivity parameters. Mathematical models obtained are discussed according to the structural properties of the studied compounds. PB - Springer Heidelberg, Heidelberg T2 - Chromatographia T1 - An approximate linear solvation energy relationships model based on Snyder's selectivity parameters. Chromatographic behavior of some 1-aralkyl-4-arylpiperazines VL - 68 IS - 5-6 SP - 453 EP - 458 DO - 10.1365/s10337-008-0711-6 ER -
@article{ author = "Andrić, Filip and Trifković, Jelena and Tešić, Živoslav Lj. and Milojković-Opsenica, Dušanka", year = "2008", abstract = "In order to elucidate the influence of the mobile phase composition on the retention of some 1-aralkyl-4-arylpiperazines, Snyder's selectivity and polarity concept for building a simple linear solvation energy relationships model of chromatographic behavior was used. Maximum variability of mobile phase selectivity was achieved by using ternary mixtures of solvents from three different corners of the Snyder selectivity triangle: methanol as a strong proton donor, acetone as a strong proton acceptor and dimethyl formamide as a dipole interactor. Water was added to keep elution strength constant. Mobile phase composition was varied using Simplex-lattice mixture design. Selectivity parameters were calculated on the basis of linear relationships between volume fractions of pure solvents and their chi (e) , chi (d) , chi (n) values. For seven-substituted 1-aralkyl-4-arylpiperazines R (M) values were measured and correlated with previously calculated selectivity parameters. Mathematical models obtained are discussed according to the structural properties of the studied compounds.", publisher = "Springer Heidelberg, Heidelberg", journal = "Chromatographia", title = "An approximate linear solvation energy relationships model based on Snyder's selectivity parameters. Chromatographic behavior of some 1-aralkyl-4-arylpiperazines", volume = "68", number = "5-6", pages = "453-458", doi = "10.1365/s10337-008-0711-6" }
Andrić, F., Trifković, J., Tešić, Ž. Lj.,& Milojković-Opsenica, D.. (2008). An approximate linear solvation energy relationships model based on Snyder's selectivity parameters. Chromatographic behavior of some 1-aralkyl-4-arylpiperazines. in Chromatographia Springer Heidelberg, Heidelberg., 68(5-6), 453-458. https://doi.org/10.1365/s10337-008-0711-6
Andrić F, Trifković J, Tešić ŽL, Milojković-Opsenica D. An approximate linear solvation energy relationships model based on Snyder's selectivity parameters. Chromatographic behavior of some 1-aralkyl-4-arylpiperazines. in Chromatographia. 2008;68(5-6):453-458. doi:10.1365/s10337-008-0711-6 .
Andrić, Filip, Trifković, Jelena, Tešić, Živoslav Lj., Milojković-Opsenica, Dušanka, "An approximate linear solvation energy relationships model based on Snyder's selectivity parameters. Chromatographic behavior of some 1-aralkyl-4-arylpiperazines" in Chromatographia, 68, no. 5-6 (2008):453-458, https://doi.org/10.1365/s10337-008-0711-6 . .